What do systematic reviews say?

Intra-articular injection of sodium hyaluronate vs corticosteroid injection

Intra-articular injection of sodium hyaluronate led to lower pain on palpation of the affected/contralateral TMJ and masticatory… compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.

• Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes

  14 days to 6 months
  Pain on palpation of the affected and contralateral TMJ and masticatory muscles presented similar frequencies regardless of the time (Analyses 1.4-1.12); no statistically significant differences reported. Point…
  1 study · 40 participants
  GRADE not reported

Intra-articular injection of sodium hyaluronate vs corticosteroid injection

Intra-articular injection of sodium hyaluronate showed no clear difference in extent of mandibular movement (maximum jaw opening, lateral and… compared with intra-articular injection of corticosteroids (betamethasone); GRADE not reported.

• Interventions for managing temporomandibular joint osteoarthritis 2012 · Cochrane All outcomes

  14 days to 6 months
  None of the mean differences between interventions for the measures of jaw movements (maximum jaw opening, lateral movement to affected side, contralateral movement, jaw protrusion; Analyses 1.16-1.27) showed…
  1 study · 40 participants
  GRADE not reported

Stabilisation splint (SS) vs Visual feedback

• Stabilisation splint therapy for temporomandibular pain dysfunction syndrome 2004 · Cochrane All outcomes

  3 months or less
  SS vs visual feedback (Monteiro 1988): both SS and visual feedback groups showed a significant decrease in lateral mandibular movement scores (P<0.01); data were unavailable for analysis.
  1 study
  GRADE not reported

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

It is very uncertain whether maxillary distraction osteogenesis changes long-term skeletal relapse/stability (horizontal movement of A-point) compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).

• Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients 2018 · Cochrane All outcomes

  5 years (long-term)
  MD 4.80 [0.41, 9.19]
  1 study · 16 participants
  Very low

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

It is very uncertain whether maxillary distraction osteogenesis changes speech: resonance (hypernasality) (deterioration/improvement) compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).

• Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients 2018 · Cochrane All outcomes

  17 months (mean)
  RR 0.11 [0.01, 1.85]
  1 study · 22 participants
  Very low

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

• Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients 2018 · Cochrane All outcomes

  12 months
  SoF (Very Low): Clinical morbidities assessed with questionnaires, follow-up 12 months; risk with orthognathic surgery 3/14; risk with maxillary distraction osteogenesis 3/15; relative effect -; 29 participants (1…
  1 study · 29 participants
  Very low

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

• Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients 2018 · Cochrane All outcomes

  up to 2 years (significant at 3 months)
  Results text (Ungraded; not in SoF): social self-esteem (subset of the Culture-Free Self-Esteem Inventory, CFSEI) - DO participants had lower social self-esteem in the first three months postoperatively, with a…
  1 study · 30 participants
  GRADE not reported

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

Maxillary distraction osteogenesis showed no clear difference in midfacial soft tissue changes (facial profile landmarks: pronasale,… compared with orthognathic surgery (conventional Le Fort I osteotomy); GRADE not reported.

• Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients 2018 · Cochrane All outcomes

  2 years
  Results text (Ungraded; not in SoF): both groups showed notable positive soft tissue changes of the upper lip and nose after maxillary advancement (39 participants). Between-group soft tissue differences at 2 years…
  1 study · 39 participants
  GRADE not reported

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

It is very uncertain whether maxillary distraction osteogenesis changes velopharyngeal function (complete velopharyngeal closure;… compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).

• Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients 2018 · Cochrane All outcomes

  17 months (mean)
  RR 1.28 [0.65, 2.52]
  1 study · 21 participants
  Very low

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

It is very uncertain whether maxillary distraction osteogenesis changes psychological status: satisfaction with life (Satisfaction With Life… compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).

• Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients 2018 · Cochrane All outcomes

  2 years
  MD 2.95 [0.14, 5.76]
  1 study · 30 participants
  Very low

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

It is very uncertain whether maxillary distraction osteogenesis changes maxillary advancement (midfacial hard tissue change; Subspinale… compared with orthognathic surgery (conventional Le Fort I osteotomy) (very low certainty).

• Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients 2018 · Cochrane All outcomes

  2 years
  MD 4.40 [0.24, 8.56]
  1 study · 39 participants
  Very low

Maxillary distraction osteogenesis vs Orthognathic surgery (conventional Le Fort I osteotomy)

Maxillary distraction osteogenesis showed no clear difference in speech: nasal emission compared with orthognathic surgery (conventional Le Fort I osteotomy); GRADE not reported.

• Maxillary distraction osteogenesis versus orthognathic surgery for cleft lip and palate patients 2018 · Cochrane All outcomes

  17 months
  RR 3.00 [0.14, 66.53]
  1 study · 22 participants
  GRADE not reported

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy dental extraction vs Post-radiotherapy dental extraction

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of healthy molar teeth vs Conservative treatment (leaving the teeth in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found

Pre-radiotherapy extraction of diseased molar teeth vs Conservative treatment (restoration of the teeth and leaving them in place during radiotherapy, with oral health education and disease prevention: oral hygiene, fluoride, diet advice)

The review found no eligible studies for this question.

• Dental extractions prior to radiotherapy to the jaws for reducing post‐radiotherapy dental complications 2013 · Cochrane All outcomes
  no estimate extracted
  0 studies
  No studies found