Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

20 questions · 20 findings · 3 reviews

No studies found 2 · 10%GRADE not reported 1 · 5%Very low 7 · 35%Low 10 · 50%Moderate 0 · 0%High 0 · 0%

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Eyes within ± 0.5 D of target refraction · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… showed no clear difference in proportion of eyes within ± 0.5 diopters of target refraction, 12… compared with LASIK with a femtosecond laser (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Mean refractive error expressed as mean spherical equivalent post‐treatment. ‐ 12 months · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism
1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Adverse effects: corneal haze · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… changes corneal haze, any time point compared with LASIK with a femtosecond laser (very low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Dry eye, any time point · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… may leads to higher dry eye, any time point compared with LASIK with a femtosecond laser (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Diffuse lamellar keratitis, any time point · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… may leads to lower diffuse lamellar keratitis, any time point compared with LASIK with a femtosecond laser (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical microkeratome vs LASIK with a femtosecond laser

Epithelial ingrowth, any time point · adults (18 years) with more than 0.5 diopters of myopia or myopic astigmatism

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) with a mechanical… changes epithelial ingrowth, any time point compared with LASIK with a femtosecond laser (very low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Proportion of eyes with uncorrected visual acuity (UCVA) of 20/20 or better post‐treatment. ‐ 12 months · patients with myopia

Laser‐assisted in‐situ keratomileusis (LASIK) may leads to higher UCVA of 20/20 or better compared with photorefractive keratectomy (PRK) (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Eyes within ± 0.5 D of target refraction · patients with myopia

Laser‐assisted in‐situ keratomileusis (LASIK) showed no clear difference in within 0.50 D of target refraction compared with photorefractive keratectomy (PRK) (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Lost one or more lines of BCVA · patients with myopia

Laser‐assisted in‐situ keratomileusis (LASIK) showed no clear difference in lost one or more lines of BCVA compared with photorefractive keratectomy (PRK) (low certainty).

1 finding from 1 review

Laser‐assisted in‐situ keratomileusis (LASIK) vs photorefractive keratectomy (PRK)

Final BCVA of 20/40 or less · patients with myopia

It is very uncertain whether laser‐assisted in‐situ keratomileusis (LASIK) changes final BCVA of 20/40 or less compared with photorefractive keratectomy (PRK) (very low certainty).

1 finding from 1 review

Intervention not reported

Uncorrected visual acuity (UCVA) of 20/20 or better · participants aged 18‐60 years with myopia ranging in severity up to 12 diopters (D)

It is very uncertain whether the intervention changes uncorrected visual acuity (UCVA) of 20/20 or better (very low certainty).

1 finding from 1 review

Intervention not reported

Uncorrected visual acuity (UCVA) of 20/40 or better · participants aged 18‐60 years with myopia ranging in severity up to 12 diopters (D)

It is very uncertain whether the intervention changes uncorrected visual acuity (UCVA) of 20/40 or better (very low certainty).

1 finding from 1 review

Intervention not reported

Proportion of participants who lost two or more lines of best‐corrected visual acuity (BCVA) · participants aged 18‐60 years with myopia ranging in severity up to 12 diopters (D)

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Eyes within ± 0.5 D of target refraction · participants aged 18‐60 years with myopia ranging in severity up to 12 diopters (D)

It is very uncertain whether the intervention changes eyes within ± 0.5 D of target refraction (very low certainty).

1 finding from 1 review