Laparoscopy probably leads to higher diagnosis before discharge compared with open appendicectomy (moderate certainty).
Laparoscopy showed no clear difference in any adverse events compared with open appendicectomy (low certainty).
Laparoscopy showed no clear difference in total length of in‐patient stay (days) compared with open appendicectomy (low certainty).
Laparoscopy probably leads to lower normal appendix removed compared with open appendicectomy (moderate certainty).
Laparoscopy probably leads to higher diagnosis before discharge compared with 'wait and see' strategy (moderate certainty).
Laparoscopy showed no clear difference in any adverse events compared with 'wait and see' strategy (moderate certainty).
Laparoscopy may leads to higher normal appendix removed compared with 'wait and see' strategy (low certainty).
Laparoscopy showed no clear difference in mortality compared with 'wait and see' strategy (low certainty).
The review found no eligible studies for this question.
Gasless laparoscopy showed no clear difference in adverse events compared with CO2 insufflation (low certainty).
The review found no eligible studies for this question.
It is very uncertain whether analysis 1 ‐ Oxidised regenerated cellulose changes incidence of adhesions ‐ de novo Incidence of adhesions at… compared with no treatment at laparoscopy (very low certainty).
It is very uncertain whether analysis 1 ‐ Oxidised regenerated cellulose changes incidence of adhesions ‐ re‐formation (or mixture) Incidence of… compared with no treatment at laparoscopy (very low certainty).
It is very uncertain whether analysis 2 ‐ Oxidised regenerated cellulose changes incidence of adhesions ‐ de novo Incidence at second‐look laparoscopy compared with no treatment at laparotomy (very low certainty).
Analysis 2 ‐ Oxidised regenerated cellulose may leads to lower incidence of adhesions ‐ re‐formation (or mixture) Incidence at… compared with no treatment at laparotomy (low certainty).
It is very uncertain whether analysis 4 ‐ Expanded polytetrafluoroethylene changes incidence of adhesions ‐ de novo Incidence at second‐look laparoscopy compared with oxidised regenerated cellulose (very low certainty).
It is very uncertain whether analysis 4 ‐ Expanded polytetrafluoroethylene changes incidence of adhesions ‐ re‐formation (or mixture) Incidence at… compared with oxidised regenerated cellulose (very low certainty).
Analysis 7 ‐ Collagen membrane with polyethylene glycol and glycerol may leads to lower incidence of adhesions ‐ de novo Incidence at second‐look laparoscopy compared with ringer's lactate (low certainty).