What do systematic reviews say?

Sulodexide (heparin plus dermatan sulphate chains) vs placebo

• Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
  Sulodexide was not associated with significant adverse events.
  1 study · 20 participants
  GRADE not reported

Sulodexide (heparin plus dermatan sulphate chains) vs placebo

• Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
  The trial by Femiano 2003 (high risk of bias) also compared sulodexide with placebo. Data were incompletely presented (ranges/totals only) precluding further analysis.
  1 study · 20 participants
  GRADE not reported

Sulodexide (heparin plus dermatan sulphate chains) vs prednisone

• Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
  A comparison between sulodexide (n=10) and prednisone (n=10) was made in a trial at high risk of bias (Femiano 2003). Data presented as ranges/totals only with no estimate of variability, precluding further analysis.…
  1 study · 20 participants
  GRADE not reported

Sulodexide (heparin plus dermatan sulphate chains) vs prednisone

• Systemic interventions for recurrent aphthous stomatitis (mouth ulcers) 2012 · Cochrane All outcomes
  Sulodexide was without significant adverse events; one significant adverse event (gastritis) was reported for the prednisone group.
  1 study · 20 participants
  GRADE not reported

Low‐level laser therapy vs Placebo (sham) laser therapy

It is very uncertain whether low-level laser therapy (photon-plus GaAlAs diode laser; 70 mW… changes patient-reported altered sensation (spontaneous or evoked:… compared with placebo (sham) laser therapy (very low certainty).

• Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes

  Lip
  MD 21.79 [5.29, 38.29]
  1 study · 13 participants
  Very low
• Interventions for iatrogenic inferior alveolar and lingual nerve injury 2014 · Cochrane All outcomes

  Chin
  MD 8.40 [3.67, 13.13]
  1 study · 13 participants
  Very low

Direct composite resin restoration vs Full-coverage metal-ceramic crown

Direct composite restoration (final restoration) showed no clear difference in clinical failure (post dislodgement) compared with full-coverage metal-ceramic crown; GRADE not reported.

• Root canal posts for the restoration of root filled teeth 2007 · Cochrane All outcomes

  36 months (3 years); dislodgement assessed at 24 months
  RR 1.85 [0.17, 19.8]
  1 study · 104 participants
  GRADE not reported

Antibiotics (systemic) vs No antibiotics, placebo, or a different type of antibiotic

The review found no eligible studies for this question.

• Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth 2013 · Cochrane All outcomes

  Minimum 12 months follow-up
  Types of antibiotics: the effect of using no antibiotics, a placebo or different types of antibiotics. Main results: No randomised or quasi-randomised controlled trials were found; no study was included in this review.
  0 studies
  No studies found

Dental repositioning vs Spontaneous re-eruption, orthodontic repositioning, or surgical repositioning

The review found no eligible studies for this question.

• Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth 2013 · Cochrane All outcomes

  Minimum 12 months follow-up
  Types of dental repositioning: to compare spontaneous re-eruption, orthodontic repositioning or surgical repositioning. Main results: No randomised or quasi-randomised controlled trials were found; no study was…
  0 studies
  No studies found

Root canal medicaments vs No medicaments, placebo, or a different type of medicament

The review found no eligible studies for this question.

• Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth 2013 · Cochrane All outcomes

  Minimum 12 months follow-up
  Types of root canal medicaments: this was compared with no medicaments, placebo and different types of medicaments. Main results: No randomised or quasi-randomised controlled trials were found; no study was included in…
  0 studies
  No studies found

Fixation (splinting) vs No splint, or a different type or duration of splint

The review found no eligible studies for this question.

• Interventions for treating traumatised permanent front teeth: luxated (dislodged) teeth 2013 · Cochrane All outcomes

  Minimum 12 months follow-up
  Types and duration of fixation: the effect of using no splint or different types of splints and their duration. Main results: No randomised or quasi-randomised controlled trials were found; no study was included in…
  0 studies
  No studies found