Findings

What do systematic reviews say?

4 questions · 4 findings · 2 reviews · Gynaecology and Fertility

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 4 · 100%Low 0 · 0%Moderate 0 · 0%High 0 · 0%

Pharmacological interventions vs pharmacological intervention

Clinical pregnancyMetformin plus liraglutide vs metformin Met + CC + L‐carnitine vs Met + CC + placebo · obese women with subfertility

It is very uncertain whether pharmacological intervention changes clinical pregnancyMetformin plus liraglutide vs metformin Met + CC +… compared with pharmacological intervention (very low certainty).

1 finding from 1 review

Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
OR 5.2 [2.59, 10.4]
1 study · 28 participants
Very low

Pharmacological interventions vs pharmacological intervention

MiscarriageMet + CC + L‐carnitine vs Met + CC + placebo · obese women with subfertility

It is very uncertain whether pharmacological intervention changes miscarriageMet + CC + L‐carnitine vs Met + CC + placebo compared with pharmacological intervention (very low certainty).

1 finding from 1 review

Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
OR 3.58 [0.73, 17.6]
1 study · 274 participants
Very low

Pharmacological interventions vs pharmacological intervention

Weight ‐ BMI changeMetformin plus liraglutide vs metformin Met + CC + L‐carnitine vs Met + CC + placebo Weight changeDexfenfluramine vs placebo Weight ‐ body fatMetformin plus liraglutide vs metformin · obese women with subfertility

1 finding from 1 review

Pharmacological and non‐pharmacological strategies for obese women with subfertility 2021 · Cochrane Headline outcomes only
no estimate extracted
1 study · 28 participants
Very low

Intervention not reported

Clinical pregnancy; type of antioxidant (natural conceptions and undergoing fertility treatments) ‐ N‐acetylcysteine versus L‐carnitine№ of participants: 164(1 RCT) · women with subfertility

It is very uncertain whether the intervention changes clinical pregnancy; type of antioxidant (natural conceptions and… (very low certainty).

1 finding from 1 review

Antioxidants for female subfertility 2020 · Cochrane Headline outcomes only
OR 0.81 [0.33, 2]
Studies not reported
Very low