Diastolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… probably leads to lower change in diastolic blood pressure (DBP, mmHg) compared with supra-gingival scaling (moderate certainty).
3 findings from 1 review
Proportion of participants diagnosed with hypertension at trial completion · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
The review found no eligible studies for this question.
1 finding from 1 review
Endothelial function (flow-mediated dilation) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… led to higher endothelial function (flow-mediated dilation) compared with supra-gingival scaling; GRADE not reported.
3 findings from 1 review
Adverse events (participants with adverse events or withdrawals due to adverse events) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
1 finding from 1 review
Heart rate · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
The review found no eligible studies for this question.
1 finding from 1 review
Plasma level of IL-6 (pg/mL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… showed no clear difference in plasma level of IL-6 (pg/mL) compared with supra-gingival scaling; GRADE not reported.
3 findings from 1 review
Systolic blood pressure (mmHg), change from baseline · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… probably leads to lower change in systolic blood pressure (SBP, mmHg) compared with supra-gingival scaling (moderate certainty).
3 findings from 1 review
Plasma level of hs-CRP (mg/L) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… showed no clear difference in plasma level of hs-CRP (mg/L) compared with supra-gingival scaling; GRADE not reported.
2 findings from 1 review
Probing pocket depth · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… led to lower pocket probing depth (PPD) compared with supra-gingival scaling; GRADE not reported.
3 findings from 1 review
Endothelial function (endothelial microparticles) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… led to lower endothelial function (endothelial microparticles) compared with supra-gingival scaling; GRADE not reported.
2 findings from 1 review
Clinical attachment level (CAL) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… led to lower clinical attachment level (CAL) compared with supra-gingival scaling; GRADE not reported.
3 findings from 1 review
Percentage of bleeding on probing (BOP) · Adults (any age/sex) with chronic periodontitis (>=5 teeth remaining; PPD >4 mm), with or without hypertension
Intensive periodontal treatment (subgingival SRP with or without… led to lower bleeding on probing (BOP) compared with supra-gingival scaling; GRADE not reported.
2 findings from 1 review
Projected Significant Caries (SiC) index · Alaska Native children (below age 18)
A simulation projected a 50% drop in the Significant Caries index for children (12.3 to 6.1) under the PDHA model (certainty not graded).
2 findings from 1 review
Projected proportion of caries-free children (5-18 years) · Alaska Native children (below age 18)
A simulation projected 0% of children aged 5-18 would be caries-free under the baseline scenario (certainty not graded).
3 findings from 1 review
Projected receipt of school-based prevention services · Alaska Native children (below age 18)
A simulation projected that over 90% of children would receive school-based prevention services under the PDHA model, up from 53% (certainty not graded).
1 finding from 1 review
Projected dental care utilisation · Alaska Native children (below age 18)
A simulation projected that the PDHA program would raise dental care utilisation from 75% to 90% (certainty not graded).
1 finding from 1 review
Projected mean DMFT (children below 5 years) · Alaska Native children (below age 18)
A simulation projected mean DMFT in children under 5 would fall from 7.4 to 4.9 under the PDHA model (certainty not graded).
1 finding from 1 review
Clinical attachment level (CAL) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
Periodontal treatment (scaling and root planing, alone or with… led to lower clinical attachment level compared with alternative (less intensive) periodontal treatment, alone or with…; GRADE not reported.
1 finding from 1 review
Low birth weight (< 2.5 kg) · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
It is very uncertain whether periodontal treatment (scaling and root planing, alone or with… changes low birth weight < 2500 g compared with alternative (less intensive) periodontal treatment, alone or with… (very low certainty).
1 finding from 1 review
Mean birth weight · Pregnant women considered to have periodontal disease (gingivitis or periodontitis) after dental examination
1 finding from 1 review