Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews

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No studies found 1 · 16.7%GRADE not reported 0 · 0%Very low 3 · 50%Low 2 · 33.3%Moderate 0 · 0%High 0 · 0%

Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder

Overall survival (absolute effect size estimates based on survival rate at 24 months) · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range) 59 to 74)Country:…

Impact of extended showed no clear difference in time to death from any cause (absolute effect size estimates based… compared with standard lymph node dissection on overall survival among patients… (low certainty).

1 finding from 1 review

Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients undergoing radical… 2019 · Cochrane Headline outcomes only
HR 0.78 [0.57, 1.07]
1 study · 401 participants
Low

Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder

Time to death from bladder cancer · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range) 59 to 74)Country:…

Impact of extended showed no clear difference in time to death from bladder cancer (absolute effect size estimates… compared with standard lymph node dissection on overall survival among patients… (low certainty).

1 finding from 1 review

Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients undergoing radical… 2019 · Cochrane Headline outcomes only
HR 0.7 [0.45, 1.07]
1 study · 401 participants
Low

Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder

Clavien‐Dindo grade ≥ 3 complications · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range) 59 to 74)Country:…

It is very uncertain whether impact of extended changes clavien‐Dindo grade ≥ 3 complications compared with standard lymph node dissection on overall survival among patients… (very low certainty).

1 finding from 1 review

Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients undergoing radical… 2019 · Cochrane Headline outcomes only
RR 1.13 [0.84, 1.52]
1 study · 401 participants
Very low

Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder

Time to recurrence · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range) 59 to 74)Country:…

It is very uncertain whether impact of extended changes time to recurrence (absolute effect size estimates based on… compared with standard lymph node dissection on overall survival among patients… (very low certainty).

1 finding from 1 review

Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients undergoing radical… 2019 · Cochrane Headline outcomes only
HR 0.84 [0.58, 1.22]
1 study · 401 participants
Very low

Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder

Clavien‐Dindo grade ≤ 2 complications8 · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range) 59 to 74)Country:…

It is very uncertain whether impact of extended changes clavien‐Dindo grade ≤ 2 complications8 compared with standard lymph node dissection on overall survival among patients… (very low certainty).

1 finding from 1 review

Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients undergoing radical… 2019 · Cochrane Headline outcomes only
RR 0.94 [0.74, 1.19]
1 study · 401 participants
Very low

Impact of extended vs standard lymph node dissection on overall survival among patients with urothelial cancer of the bladder

Disease‐specific quality of life · Partcipants with bladder cancer undergoing radical cystectomy (male n = 314, female n = 87; age (interquartile range) 59 to 74)Country:…

The review found no eligible studies for this question.

1 finding from 1 review

Extended versus standard lymph node dissection for urothelial carcinoma of the bladder in patients undergoing radical… 2019 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found