Findings

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6 questions · 7 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 7 · 100%High 0 · 0%

Impact of Xpert MTB/RIF vs smear microscopy

All‐cause mortality among participants · people being investigated for tuberculosis (TB)

Impact of Xpert MTB/RIF showed no clear difference in all‐cause mortality among participants compared with smear microscopy (moderate certainty).

1 finding from 1 review

Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis 2021 · Cochrane Headline outcomes only
RR 0.89 [0.75, 1.05]
5 studies · 9932 participants
Moderate

Impact of Xpert MTB/RIF vs smear microscopy

All‐cause mortality at 6 months (subgroup) · people being investigated for tuberculosis (TB)

Impact of Xpert MTB/RIF showed no clear difference in all‐cause mortality at 6 months (subgroup) compared with smear microscopy (moderate certainty).

2 findings from 1 review

Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis 2021 · Cochrane Headline outcomes only
RR 0.98 [0.78, 1.22]
3 studies · 8143 participants
Moderate
Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis 2021 · Cochrane Headline outcomes only
OR 0.8 [0.67, 0.96]
5 studies · 5855 participants
Moderate

Impact of Xpert MTB/RIF vs smear microscopy

Successful treatment outcome in participants treated for tuberculosis · people being investigated for tuberculosis (TB)

Impact of Xpert MTB/RIF showed no clear difference in successful treatment outcome in participants treated for tuberculosis compared with smear microscopy (moderate certainty).

1 finding from 1 review

Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis 2021 · Cochrane Headline outcomes only
OR 1.1 [0.95, 1.26]
3 studies · 4802 participants
Moderate

Impact of Xpert MTB/RIF vs smear microscopy

Proportion of participants who were treated for tuberculosis · people being investigated for tuberculosis (TB)

Impact of Xpert MTB/RIF showed no clear difference in proportion of participants who were treated for tuberculosis compared with smear microscopy (moderate certainty).

1 finding from 1 review

Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis 2021 · Cochrane Headline outcomes only
RR 1.1 [0.98, 1.23]
5 studies · 8793 participants
Moderate

Impact of Xpert MTB/RIF vs smear microscopy

Pre‐treatment loss to · people being investigated for tuberculosis (TB)

Impact of Xpert MTB/RIF probably leads to lower pre‐treatment loss to compared with smear microscopy (moderate certainty).

1 finding from 1 review

Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis 2021 · Cochrane Headline outcomes only
RR 0.59 [0.41, 0.85]
3 studies · 1217 participants
Moderate

Impact of Xpert MTB/RIF vs smear microscopy

Treated participants with bacteriological confirmation of tuberculosis · people being investigated for tuberculosis (TB)

Impact of Xpert MTB/RIF probably leads to higher treated participants with bacteriological confirmation of tuberculosis compared with smear microscopy (moderate certainty).

1 finding from 1 review

Impact of the diagnostic test Xpert MTB/RIF on patient outcomes for tuberculosis 2021 · Cochrane Headline outcomes only
RR 1.44 [1.29, 1.61]
6 studies · 2068 participants
Moderate