Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Epilepsy

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No studies found 4 · 57.1%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 1 · 14.3%High 0 · 0%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Immunomodulatory interventions vs placebo · 50% or greater reduction in seizure frequency ‐ ITT analysis
  Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
  RR 2.3
  3 studies · 172 participants
  Moderate
Direct match · question page
- Immunomodulatory interventions vs placebo · Seizure freedom
  Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
Direct match · question page
- Immunomodulatory interventions vs placebo · Treatment withdrawal
  Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
  RR 1.04
  3 studies · 172 participants
  Low
Direct match · question page
- Immunomodulatory interventions vs placebo · Cognitive effects
  Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found
Direct match · question page
- Immunomodulatory interventions vs placebo · Quality of life
  Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

Immunomodulatory interventions vs placebo

Seizure freedom · people with focal epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Immunomodulatory interventions vs placebo

50% or greater reduction in seizure frequency · people with focal epilepsy

Immunomodulatory interventions probably leads to higher 50% or greater reduction in seizure frequency ‐ ITT analysis compared with placebo (moderate certainty).

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
RR 2.3
3 studies · 172 participants
Moderate

Immunomodulatory interventions vs placebo

Adverse events of glucocorticoids and immunosuppressive drugs · people with focal epilepsy

Immunomodulatory interventions may leads to higher adverse events of glucocorticoids and immunosuppressive drugs compared with placebo (low certainty).

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
RR 1.16
1 study · 66 participants
Low

Immunomodulatory interventions vs placebo

Treatment withdrawal · people with focal epilepsy

Immunomodulatory interventions may leads to higher treatment withdrawal compared with placebo (low certainty).

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
RR 1.04
3 studies · 172 participants
Low

Immunomodulatory interventions vs placebo

Allergic reaction · people with focal epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Immunomodulatory interventions vs placebo

Cognitive effects · people with focal epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Immunomodulatory interventions vs placebo

Quality of life · people with focal epilepsy

The review found no eligible studies for this question.

1 finding from 1 review

Immunomodulatory interventions for focal epilepsy 2023 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found