Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 1 · 14.3%Very low 1 · 14.3%Low 4 · 57.1%Moderate 1 · 14.3%High 0 · 0%

INTERMITTENT (EARLY‐BASED) vs MAINTENANCE THERAPY

Global state: average score: long term (+ 26 weeks) Global Assessment Scale (GAS). Scale from: 0 to 100. · patients with schizophrenia

1 finding from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 82 participants
Low

INTERMITTENT (EARLY‐BASED) vs MAINTENANCE THERAPY

Mental state · patients with schizophrenia

1 finding from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
1 study · 26 participants
Very low

INTERMITTENT (EARLY‐BASED) vs MAINTENANCE THERAPY

Adverse effects: tardive dyskinesia: long term (+ 26 weeks) as defined in each study · patients with schizophrenia

INTERMITTENT (EARLY‐BASED) showed no clear difference in adverse effects: tardive dyskinesia: long term (+26 weeks) as… compared with MAINTENANCE THERAPY (low certainty).

1 finding from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
RR 0.56 [0.19, 1.7]
1 study · 30 participants
Low

INTERMITTENT (EARLY‐BASED) vs MAINTENANCE THERAPY

Cost‐effectiveness · patients with schizophrenia

1 finding from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

INTERMITTENT (EARLY‐BASED) vs MAINTENANCE THERAPY

Leaving the study early/ loss to · patients with schizophrenia

INTERMITTENT (EARLY‐BASED) may leads to higher leaving the study early/loss to compared with MAINTENANCE THERAPY (low certainty).

1 finding from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
RR 1.67 [1.17, 2.37]
5 studies · 562 participants
Low

INTERMITTENT (EARLY‐BASED) vs MAINTENANCE THERAPY

Relapse · patients with schizophrenia

INTERMITTENT (EARLY‐BASED) may leads to higher relapse: long term (+ 26 weeks) as defined in each study compared with MAINTENANCE THERAPY (low certainty).

1 finding from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
RR 2.33 [1.32, 4.12]
2 studies · 155 participants
Low

INTERMITTENT (EARLY‐BASED) vs MAINTENANCE THERAPY

Hospital admissions · patients with schizophrenia

INTERMITTENT (EARLY‐BASED) probably leads to higher hospitalisation: long term (+ 26 weeks) as defined in each study compared with MAINTENANCE THERAPY (moderate certainty).

1 finding from 1 review

Intermittent drug techniques for schizophrenia 2013 · Cochrane Headline outcomes only
RR 1.16 [1.33, 2.08]
5 studies · 625 participants
Moderate