What do systematic reviews say?

ICD plus optimal medical therapy vs optimal medical therapy alone

The review found no eligible studies for this question.

• Implantable cardiac defibrillators for people with non‐ischaemic cardiomyopathy 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

ICD plus optimal medical therapy vs optimal medical therapy alone

The review found no eligible studies for this question.

• Implantable cardiac defibrillators for people with non‐ischaemic cardiomyopathy 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found

ICD plus optimal medical therapy vs optimal medical therapy alone

ICD plus optimal medical therapy leads to lower all‐cause mortality (HR) ‐ main analysisa 16.5 to 67.6 months compared with optimal medical therapy alone (high certainty).

• Implantable cardiac defibrillators for people with non‐ischaemic cardiomyopathy 2018 · Cochrane Headline outcomes only
  HR 0.78 [0.66, 0.92]
  6 studies · 3128 participants
  High

ICD plus optimal medical therapy vs optimal medical therapy alone

ICD plus optimal medical therapy showed no clear difference in cardiovascular mortality (RR)b 22.8 to 67.6 months compared with optimal medical therapy alone (moderate certainty).

• Implantable cardiac defibrillators for people with non‐ischaemic cardiomyopathy 2018 · Cochrane Headline outcomes only
  RR 0.75 [0.46, 1.21]
  4 studies · 1781 participants
  Moderate

ICD plus optimal medical therapy vs optimal medical therapy alone

ICD plus optimal medical therapy leads to lower sudden cardiac death (HR)a 24 to 67.6 months compared with optimal medical therapy alone (high certainty).

• Implantable cardiac defibrillators for people with non‐ischaemic cardiomyopathy 2018 · Cochrane Headline outcomes only
  HR 0.45 [0.29, 0.7]
  3 studies · 1677 participants
  High

ICD plus optimal medical therapy vs optimal medical therapy alone

• Implantable cardiac defibrillators for people with non‐ischaemic cardiomyopathy 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 1116 participants
  Moderate

ICD plus optimal medical therapy vs optimal medical therapy alone

ICD plus optimal medical therapy showed no clear difference in noncardiovascular mortality (RR)b 22.8 to 67.6 months compared with optimal medical therapy alone (moderate certainty).

• Implantable cardiac defibrillators for people with non‐ischaemic cardiomyopathy 2018 · Cochrane Headline outcomes only
  RR 1.17 [0.81, 1.68]
  4 studies · 1781 participants
  Moderate

ICD plus optimal medical therapy vs optimal medical therapy alone

• Implantable cardiac defibrillators for people with non‐ischaemic cardiomyopathy 2018 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 561 participants
  Moderate