Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

25 questions · 25 findings · 2 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 6 · 24%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 16%Moderate 5 · 20%High 10 · 40%

Hyperbaric oxygen vs air breathing to enhance the effectiveness of radiotherapy

Failure of local tumour control ‐ not reported · People undergoing radiation therapy for head and neck cancer

Hyperbaric oxygen probably leads to lower failure of local tumour control (local control) compared with air breathing to enhance the effectiveness of radiotherapy (moderate certainty).

1 finding from 1 review

Hyperbaric oxygen vs control without HBOT

Death at 1 year · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…

Hyperbaric oxygen therapy (HBOT) showed no clear difference in death at 1 year compared with control without HBOT (low certainty).

1 finding from 1 review

Hyperbaric oxygen vs control without HBOT

Complete or substantial improvement of condition · any person with radiation tissue injury arising later than 6 months after irradiation (LRTI), including dysfunction or necrosis of any…

Hyperbaric oxygen therapy (HBOT) may leads to higher complete or substantial improvement of condition compared with control without HBOT (low certainty).

1 finding from 1 review