Caries increment in permanent teeth · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
It is very uncertain whether chlorhexidine varnish (10% and 40%) changes caries increment in permanent dentition (DMFS; higher values… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Elevated mutans streptococci levels (>=4 with caries screen; high vs low) · Children and adolescents below 18 years at study start (included studies: children from birth to 15 years), with mixed, permanent or…
It is very uncertain whether chlorhexidine varnish (10%) changes elevated mutans streptococci levels (>=4 with caries screen; high vs… compared with placebo or no treatment (very low certainty).
1 finding from 1 review
Reduction in contamination of aerosols on operator's face shield/mask (RCTs) · People undergoing aerosol-generating procedures (AGPs) in a dental setting
High-volume evacuation (HVE) showed no clear difference in reduction in contamination of aerosols on operator's face… compared with no HVE; GRADE not reported.
1 finding from 1 review
Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling at 40 cm from mouth · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with conventional dental suction (low-volume evacuator / saliva ejector) (very low certainty).
1 finding from 1 review
MD -2.30 [-5.32, 0.72]
1 study · 6 participants
Very low
Reduction in level of contamination in aerosols (CFU) at more than 1 foot from oral cavity (CCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting
High-volume evacuation (HVE) led to lower reduction in level of contamination in aerosols (CFU) at more than 1… compared with no HVE; GRADE not reported.
1 finding from 1 review
Reduction in level of contamination in aerosols (CFU) at less than 1 foot from oral cavity (CCTs) · People undergoing aerosol-generating procedures (AGPs) in a dental setting
High-volume evacuation (HVE) showed no clear difference in reduction in level of contamination in aerosols (CFU) at less than 1… compared with no HVE; GRADE not reported.
1 finding from 1 review
Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling and air polishing at more than 1 foot from oral cavity (RCT) · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with no HVE (very low certainty).
1 finding from 1 review
Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling and air polishing at less than 1 foot (~30 cm) from oral cavity (RCTs) · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with no HVE (very low certainty).
1 finding from 1 review
Reduction in level of contamination in aerosols (CFU) during ultrasonic scaling at 150 cm from mouth · People undergoing aerosol-generating procedures (AGPs) in a dental setting
It is very uncertain whether high-volume evacuation (HVE) changes reduction in level of contamination in aerosols (CFU) during… compared with conventional dental suction (low-volume evacuator / saliva ejector) (very low certainty).
1 finding from 1 review
MD -2.20 [-14.01, 9.61]
1 study · 6 participants
Very low
Wound infection · Adults with mandibular third molars requiring removal
It is very uncertain whether high-volume irrigation (~175 mL) changes wound infection compared with low-volume irrigation (~25 mL) (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults with mandibular third molars requiring removal
It is very uncertain whether high-volume irrigation (~175 mL) changes alveolar osteitis compared with low-volume irrigation (~25 mL) (very low certainty).
1 finding from 1 review
Adverse effects (loose stools, diarrhoea) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Adverse effects were not reported in a usable format, but the reported rates of loose stools and diarrhoea were very similar between groups. There were no serious adverse effects during the study. Milgrom 2009.
1 study · 94 participants
GRADE not reported
Caries in primary teeth (mean number of decayed primary teeth) · Infants (primary teeth; baseline about 9 to 15 months)
1 finding from 1 review
Wound infection · Adults with mandibular third molars requiring removal
It is very uncertain whether mechanical (high-volume) irrigation changes wound infection compared with manual (low-volume) irrigation (very low certainty).
1 finding from 1 review
Presence of dry socket · Adults with mandibular third molars requiring removal
It is very uncertain whether mechanical (high-volume) irrigation changes alveolar osteitis compared with manual (low-volume) irrigation (very low certainty).
1 finding from 1 review
Oral mucositis (any severity) · Adults with cancer receiving treatment
1 finding from 1 review
Total mortality · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Higher total dose radiotherapy (76.8 Gy over 6.4 weeks) showed no clear difference in total mortality compared with conventional/standard total dose radiotherapy (72 Gy); GRADE not reported.
1 finding from 1 review
HR 1.08 [0.69, 1.70]
1 study
GRADE not reported
Locoregional control · People with primary squamous cell carcinoma of the oral cavity (ICD-O C01-C06) or oropharynx (ICD-O C09-C10); head and neck cancer trials…
Higher total dose radiotherapy (76.8 Gy over 6.4 weeks) showed no clear difference in locoregional control compared with conventional/standard total dose radiotherapy (72 Gy); GRADE not reported.
1 finding from 1 review
HR 0.78 [0.55, 1.11]
1 study
GRADE not reported
Discomfort associated with the procedure · People with dental caries in primary teeth (mainly children)
ART using high-viscosity glass ionomer cement (H-GIC), hand… showed no clear difference in participant experience (discomfort during procedure) compared with conventional treatment using H-GIC (rotary instruments); GRADE not reported.
1 finding from 1 review
Pain (during procedure, primary dentition) · People with dental caries in primary teeth (mainly children)
ART using high-viscosity glass ionomer cement (H-GIC), hand… showed no clear difference in pain (during procedure, primary dentition) compared with conventional treatment using H-GIC (rotary instruments) (low certainty).
1 finding from 1 review