Findings

What do systematic reviews say?

8 questions · 8 findings · 2 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

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No studies found 3 · 37.5%GRADE not reported 0 · 0%Very low 2 · 25%Low 0 · 0%Moderate 0 · 0%High 3 · 37.5%

Intervention not reported

Intervention: high‐dose radiotherapy Comparison: low‐dose radiotherapy Outcome: neurocognitive impairment at 2 years after treatment · people with glioma surviving at least two years

It is very uncertain whether the intervention changes intervention: high‐dose radiotherapy Comparison: low‐dose… (very low certainty).

1 finding from 1 review

Long‐term neurocognitive and other side effects of radiotherapy, with or without chemotherapy, for glioma 2019 · Cochrane Headline outcomes only
RR 0.53 [0.06, 4.85]
1 study · 65 participants
Very low

Intervention not reported

Intervention: high‐dose radiotherapy Comparison: low‐dose radiotherapy Outcome: neurocognitive impairment at 5 years after treatment · people with glioma surviving at least two years

It is very uncertain whether the intervention changes intervention: high‐dose radiotherapy Comparison: low‐dose… (very low certainty).

1 finding from 1 review

Long‐term neurocognitive and other side effects of radiotherapy, with or without chemotherapy, for glioma 2019 · Cochrane Headline outcomes only
RR 0.16 [0.01, 3.2]
1 study · 38 participants
Very low

Intervention not reported

Overall survival · people with non‐rhabdomyosarcoma soft tissue sarcoma

The intervention showed no clear difference in overall survival (high certainty).

1 finding from 1 review

Autologous hematopoietic stem cell transplantation following high‐dose chemotherapy for nonrhabdomyosarcoma soft… 2017 · Cochrane Headline outcomes only
HR 1.26 [0.7, 2.29]
1 study · 83 participants
High

Intervention not reported

Treatment‐related mortality · people with non‐rhabdomyosarcoma soft tissue sarcoma

1 finding from 1 review

Autologous hematopoietic stem cell transplantation following high‐dose chemotherapy for nonrhabdomyosarcoma soft… 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 83 participants
High

Intervention not reported

Disease‐free survival · people with non‐rhabdomyosarcoma soft tissue sarcoma

The review found no eligible studies for this question.

1 finding from 1 review

Autologous hematopoietic stem cell transplantation following high‐dose chemotherapy for nonrhabdomyosarcoma soft… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Progression‐free survival · people with non‐rhabdomyosarcoma soft tissue sarcoma

The intervention showed no clear difference in progression‐free survival (high certainty).

1 finding from 1 review

Autologous hematopoietic stem cell transplantation following high‐dose chemotherapy for nonrhabdomyosarcoma soft… 2017 · Cochrane Headline outcomes only
HR 1.34 [0.81, 2.2]
1 study · 83 participants
High

Intervention not reported

Non‐hematologic toxicity grade 3 to 4 · people with non‐rhabdomyosarcoma soft tissue sarcoma

The review found no eligible studies for this question.

1 finding from 1 review

Autologous hematopoietic stem cell transplantation following high‐dose chemotherapy for nonrhabdomyosarcoma soft… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Intervention not reported

Health‐related quality of life · people with non‐rhabdomyosarcoma soft tissue sarcoma

The review found no eligible studies for this question.

1 finding from 1 review

Autologous hematopoietic stem cell transplantation following high‐dose chemotherapy for nonrhabdomyosarcoma soft… 2017 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found