Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

38 questions · 38 findings · 6 reviews

No studies found 0 · 0%GRADE not reported 1 · 2.6%Very low 8 · 21.1%Low 11 · 28.9%Moderate 16 · 42.1%High 2 · 5.3%

Eradication therapy combined with periodontal therapy vs eradication therapy alone

Eradication rate of gastric H. pylori · patients with gastric Helicobacter pylori infection

Eradication therapy combined with periodontal therapy probably leads to higher eradication rate of gastric H. pylori compared with eradication therapy alone (moderate certainty).

1 finding from 1 review

H. pylori eradication therapy vs control

Incidence of gastric cancer ‐ modified ITT analysis Histological examination · healthy asymptomatic H. pylori‐infected individuals

H. pylori eradication therapy probably leads to lower incidence of gastric cancer ‐ modified ITT analysisHistological… compared with control (moderate certainty).

1 finding from 1 review

H. pylori eradication therapy vs control

Incidence of oesophageal squamous cell carcinoma ‐ modified ITT analysis · healthy asymptomatic H. pylori‐infected individuals

H. pylori eradication therapy showed no clear difference in incidence of oesophageal squamous cell carcinoma ‐ modified ITT… compared with control (moderate certainty).

1 finding from 1 review

Intervention not reported

H. pylori eradication therapy plus ulcer healing drug versus ulcer healing drug alone · people with Helicobacter pylori‐positive peptic ulcer

The intervention may leads to lower H. pylori eradication therapy plus ulcer healing drug versus ulcer… (low certainty).

1 finding from 1 review

Intervention not reported

H. pylori eradication therapy versus no active treatment · people with Helicobacter pylori‐positive peptic ulcer

The intervention may leads to lower H. pylori eradication therapy versus no active treatment (low certainty).

1 finding from 1 review

Intervention not reported

H. pylori eradication therapy versus ulcer healing drug alone · prevention of recurrence in people with Helicobacter pylori‐positive peptic ulcer

It is very uncertain whether the intervention changes H. pylori eradication therapy versus ulcer healing drug alone (very low certainty).

1 finding from 1 review

Intervention not reported

H. pylori eradication therapy versus no active treatment · prevention of recurrence in people with Helicobacter pylori‐positive peptic ulcer

It is very uncertain whether the intervention changes H. pylori eradication therapy versus no active treatment (very low certainty).

1 finding from 1 review

Eradication therapy combined with periodontal therapy vs eradication therapy alone

Non‐recurrence rate of gastric H. pylori · patients with gastric Helicobacter pylori infection

Eradication therapy combined with periodontal therapy may leads to higher non‐recurrence rate of gastric H. pylori compared with eradication therapy alone (low certainty).

1 finding from 1 review