Live birth rate per woman · women undergoing assisted reproductive technology (ART)
GnRH antagonist showed no clear difference in live birth rate per woman randomised compared with long‐course GnRH agonist (moderate certainty).
1 finding from 1 review
OHSS per woman randomised (any grade) · women undergoing assisted reproductive technology (ART)
GnRH antagonist probably leads to lower OHSS per woman randomised (any grade) compared with long‐course GnRH agonist (moderate certainty).
1 finding from 1 review
Ongoing pregnancy · women undergoing assisted reproductive technology (ART)
GnRH antagonist showed no clear difference in ongoing pregnancy rate per woman randomised compared with long‐course GnRH agonist (moderate certainty).
1 finding from 1 review
Clinical pregnancy rate · women undergoing assisted reproductive technology (ART)
GnRH antagonist showed no clear difference in clinical pregnancy rate per woman randomised compared with long‐course GnRH agonist (moderate certainty).
1 finding from 1 review
Miscarriage · women undergoing assisted reproductive technology (ART)
GnRH antagonist showed no clear difference in miscarriage rate per woman randomised compared with long‐course GnRH agonist (moderate certainty).
1 finding from 1 review
Cycle cancellation due to poor ovarian response · women undergoing assisted reproductive technology (ART)
GnRH antagonist probably leads to higher cycle cancellation due to poor ovarian response compared with long‐course GnRH agonist (moderate certainty).
1 finding from 1 review
Live birth or ongoing pregnancy · assisted reproduction technology cycles
3 findings from 1 review
Total oocytes ‐ Normoresponders ‐ Donor oocytes ‐ Early phase stimulation protocol ‐ Fresh embryo transfer (MPA 10 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review
Total oocytes ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review
MII oocytes ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review
Duration of stimulation (days) ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review
Total dose of gonadotropins (IU) ‐ Normoresponders ‐ Donor oocytes ‐ Early ophase stimulation protocol ‐ Fresh embryo transfer (MPA 10 mg/day versus GnRH antagonists · assisted reproduction technology cycles
1 finding from 1 review
Oocyte pick‐up cancellation · assisted reproduction technology cycles
Summary of findings table ‐ Progestogens showed no clear difference in oocyte pick‐up cancellation ‐ total compared with gnRH antagonists (low certainty).
3 findings from 1 review
OR 0.92 [0.42, 2.01]
3 studies · 648 participants
Low
OR 0.84 [0.28, 2.55]
2 studies · 534 participants
GRADE not reported
OR 1 [0.33, 3.06]
1 study · 114 participants
GRADE not reported
Total dose of gonadotropins (IU) ‐ PCOS (high‐responders) ‐ Own oocytes ‐ Early phase stumulation protocol ‐ Frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review
Moderate or severe OHSS ‐ Poor‐responders (MPA 10 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol · assisted reproduction technology cycles
1 finding from 1 review
no estimate extracted
1 study · 1 participants
GRADE not reported
Moderate or severe OHSS ‐ Normoresponders ‐ Donor oocytes ‐ Early phase stimulation protocol ‐ Fresh embryo transfer (MPA 10 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
1 finding from 1 review
Live birth or ongoing pregnancy sensitivity analysis ‐ PCOS (high‐responders) ‐ own oocytes ‐ early phase stimulation protocol ‐ frozen embryo transfer (micronised progesterone 100 mg/day versus GnRH antagonists) · assisted reproduction technology cycles
Summary of findings table ‐ Progestogens showed no clear difference in live birth or ongoing pregnancy sensitivity analysis ‐ PCOS… compared with gnRH antagonists; GRADE not reported.
1 finding from 1 review
Oocyte pick‐up cancellation sensitivity analysis ‐ Normoresponders (MPA 10 mg versus GnRH antagonists) ‐ Donor oocytes ‐ Early phase stimulation protocol ‐ Fresh embryo transfer · assisted reproduction technology cycles
Summary of findings table ‐ Progestogens showed no clear difference in oocyte pick‐up cancellation sensitivity analysis ‐ Normoresponders… compared with gnRH antagonists; GRADE not reported.
1 finding from 1 review
Oocyte pick‐up cancellation sensitivity analysis ‐ Normoresponders (micronised progesterone 200 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Fresh embryo transfer · assisted reproduction technology cycles
Summary of findings table ‐ Progestogens showed no clear difference in oocyte pick‐up cancellation sensitivity analysis ‐ Normoresponders… compared with gnRH antagonists; GRADE not reported.
1 finding from 1 review
Oocyte pick‐up cancellation sensitivity analysis ‐ PCOS (high‐responders)(micronised progesterone 100 mg versus GnRH antagonists) ‐ Own oocytes ‐ Early phase stimulation protocol ‐ Frozen embryo transfer · assisted reproduction technology cycles
Summary of findings table ‐ Progestogens showed no clear difference in oocyte pick‐up cancellation sensitivity analysis ‐ PCOS… compared with gnRH antagonists; GRADE not reported.
1 finding from 1 review