Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 2 · 28.6%Moderate 5 · 71.4%High 0 · 0%

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

Infectious complications · critically ill patients or receiving major surgery

Glutamine‐supplemented nutrition probably leads to lower infectious complications compared with non‐supplemented nutrition (moderate certainty).

1 finding from 1 review

Glutamine supplementation for critically ill adults 2014 · Cochrane Headline outcomes only
RR 0.79 [0.71, 0.87]
33 studies · 2303 participants
Moderate

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

Short‐term mortality (within hospital stay or closest to one month) · critically ill patients or receiving major surgery

Glutamine‐supplemented nutrition showed no clear difference in short‐term mortality (within hospital stay or closest to one month) compared with non‐supplemented nutrition (low certainty).

1 finding from 1 review

Glutamine supplementation for critically ill adults 2014 · Cochrane Headline outcomes only
RR 0.89 [0.78, 1.02]
36 studies · 3454 participants
Low

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

Long‐term mortality (closest to six month) · critically ill patients or receiving major surgery

Glutamine‐supplemented nutrition showed no clear difference in long‐term mortality (closest to six month) compared with non‐supplemented nutrition (moderate certainty).

1 finding from 1 review

Glutamine supplementation for critically ill adults 2014 · Cochrane Headline outcomes only
RR 1 [0.89, 1.12]
11 studies · 2277 participants
Moderate

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

Length of hospital stay · critically ill patients or receiving major surgery

1 finding from 1 review

Glutamine supplementation for critically ill adults 2014 · Cochrane Headline outcomes only
no estimate extracted
36 studies · 2963 participants
Low

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

Duration of ICU stay · critically ill patients or receiving major surgery

1 finding from 1 review

Glutamine supplementation for critically ill adults 2014 · Cochrane Headline outcomes only
no estimate extracted
22 studies · 2284 participants
Moderate

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

Duration of mechanical ventilation · critically ill patients or receiving major surgery

1 finding from 1 review

Glutamine supplementation for critically ill adults 2014 · Cochrane Headline outcomes only
no estimate extracted
14 studies · 1297 participants
Moderate

Glutamine‐supplemented nutrition vs non‐supplemented nutrition

Serious adverse events · critically ill patients or receiving major surgery

Glutamine‐supplemented nutrition showed no clear difference in serious adverse events compared with non‐supplemented nutrition (moderate certainty).

1 finding from 1 review

Glutamine supplementation for critically ill adults 2014 · Cochrane Headline outcomes only
RR 1.4 [0.77, 2.57]
2 studies · 856 participants
Moderate