evidencegaps
Findings

What do systematic reviews say?

Refine by population, intervention, comparison or outcome
More filters
Evidence found and GRADE certainty

42 questions · 42 findings · 1 reviews

Sort:Best matchNewestHighest certaintyDownload CSV
No studies found 18 · 42.9%GRADE not reported 0 · 0%Very low 0 · 0%Low 6 · 14.3%Moderate 11 · 26.2%High 7 · 16.7%

Febuxostat 80 mg/day vs placebo

Serious adverse events · people with chronic gout

Febuxostat 80 mg/day showed no clear difference in serious Adverse Events compared with placebo (moderate certainty).

1 finding from 1 review

Febuxostat 80 mg/day vs placebo

Withdrawals due to adverse events · people with chronic gout

Febuxostat 80 mg/day showed no clear difference in discontinuations due to adverse events compared with placebo (moderate certainty).

1 finding from 1 review

Febuxostat 80 mg/day vs allopurinol

Serum uric acid <6.0 mg/dL at final visit · people with chronic gout

Febuxostat 80 mg/day may leads to higher serum uric acid <6.0 mg/dL at final visit compared with allopurinol (low certainty).

1 finding from 1 review

Febuxostat 80 mg/day vs allopurinol

Serious adverse events · people with chronic gout

Febuxostat 80 mg/day showed no clear difference in serious Adverse Events compared with allopurinol (moderate certainty).

1 finding from 1 review

Febuxostat 80 mg/day vs allopurinol

Withdrawals due to adverse events · people with chronic gout

Febuxostat 80 mg/day showed no clear difference in discontinuations due to adverse events compared with allopurinol (moderate certainty).

1 finding from 1 review

Febuxostat 80 mg/day vs placebo

Acute gout attacks · people with chronic gout

Febuxostat 80 mg/day showed no clear difference in incidence of gout flares compared with placebo (low certainty).

1 finding from 1 review

Febuxostat 80 mg/day vs placebo

Serum uric acid <6.0 mg/dL at final visit · people with chronic gout

Febuxostat 80 mg/day may leads to higher serum uric acid <6.0 mg/dL at final visit compared with placebo (low certainty).

1 finding from 1 review

Febuxostat 40 mg/day vs placebo

Acute gout attacks · people with chronic gout

Febuxostat 40 mg/day showed no clear difference in incidence of gout flares compared with placebo (low certainty).

1 finding from 1 review

Febuxostat 40 mg/day vs placebo

Serum uric acid <6.0 mg/dL at final visit · people with chronic gout

Febuxostat 40 mg/day may leads to higher serum uric acid <6.0 mg/dL at final visit compared with placebo (low certainty).

1 finding from 1 review

Febuxostat 40 mg/day vs allopurinol

Serum uric acid <6.0 mg/dL at final visit · people with chronic gout

Febuxostat 40 mg/day showed no clear difference in serum uric acid <6.0 mg/dL at final visit compared with allopurinol (moderate certainty).

1 finding from 1 review