Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

20 questions · 20 findings · 3 reviews · Schizophrenia

No studies found 3 · 15%GRADE not reported 2 · 10%Very low 8 · 40%Low 7 · 35%Moderate 0 · 0%High 0 · 0%

ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs usual care

Family outcome: Burden ‐ not improved/worse (objective burden related to self‐sufficiency) · patients with schizophrenia

It is very uncertain whether ANY FAMILY BASED INTERVENTIONS (>5 sessions) changes family outcome: Burden ‐ not improved/worse (objective burden… compared with STANDARD CARE (very low certainty).

1 finding from 1 review

ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs usual care

Social functioning: Specific ‐ unemployed ‐ at about 1 year · patients with schizophrenia

ANY FAMILY BASED INTERVENTIONS (>5 sessions) showed no clear difference in social functioning: Specific ‐ unemployed ‐ at about 1 year compared with STANDARD CARE (low certainty).

1 finding from 1 review

ANY FAMILY BASED INTERVENTIONS (>5 sessions) vs usual care

Social functioning: Specific ‐ unable to live independently ‐ at about 1 year · patients with schizophrenia

ANY FAMILY BASED INTERVENTIONS (>5 sessions) showed no clear difference in social functioning: Specific ‐ unable to live independently ‐ at… compared with STANDARD CARE (low certainty).

1 finding from 1 review

Group C other: family treatment vs enhanced care

Prodromal symptoms: transition to psychosis FACT Long‐term · people in the prodromal stage of psychosis

It is very uncertain whether group C other: family treatment changes prodromal symptoms: transition to psychosis FACT Long‐term compared with enhanced care (very low certainty).

1 finding from 1 review

Group C other: family treatment vs enhanced care

Global state: antipsychotic prescriptions (events) · people in the prodromal stage of psychosis

It is very uncertain whether group C other: family treatment changes global state: antipsychotic prescriptions (events) compared with enhanced care (very low certainty).

1 finding from 1 review

Group C other: family treatment vs enhanced care

Satisfaction with treatment: leaving the study early FACT Long‐term · people in the prodromal stage of psychosis

It is very uncertain whether group C other: family treatment changes satisfaction with treatment: leaving the study early FACT Long‐term compared with enhanced care (very low certainty).

1 finding from 1 review

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)

Service use: Number of participants needing admission · Adolescents with psychosis

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) showed no clear difference in service use: Number of participants needing admission compared with NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term) (low certainty).

1 finding from 1 review

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) vs NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term)

Leaving the study early · Adolescents with psychosis

PSYCHOEDUCATIONAL (PE) + MULTIFAMILY TREATMENT (MFT) showed no clear difference in leaving the study early: For any reason compared with NONSTRUCTURED GROUP THERAPY (NSGT, all long‐term) (low certainty).

1 finding from 1 review