What do systematic reviews say?

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

It is very uncertain whether whole gland primary cryotherapy changes time to death from prostate cancer (absolute effects:… compared with external beam radiotherapy (EBRT) (very low certainty).

• Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
  HR 1 [0.11, 9.45]
  2 studies · 293 participants
  Very low

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

• Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 195 participants
  Very low

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

• Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 195 participants
  Very low

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

• Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 195 participants
  Very low

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

It is very uncertain whether whole gland primary cryotherapy changes major adverse events compared with external beam radiotherapy (EBRT) (very low certainty).

• Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
  RR 0.91 [0.47, 1.78]
  2 studies · 293 participants
  Very low

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

It is very uncertain whether whole gland primary cryotherapy changes time to death from any cause (absolute effects: overall mortality) compared with external beam radiotherapy (EBRT) (very low certainty).

• Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
  HR 0.99 [0.05, 18.79]
  2 studies · 293 participants
  Very low

Whole gland primary cryotherapy vs external beam radiotherapy (EBRT)

The review found no eligible studies for this question.

• Primary cryotherapy for localised or locally advanced prostate cancer 2018 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  No studies found