Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

442 questions · 468 findings · 55 reviews

No studies found 96 · 20.5%GRADE not reported 54 · 11.5%Very low 172 · 36.8%Low 87 · 18.6%Moderate 40 · 8.5%High 19 · 4.1%

Open surgical exposure vs Closed surgical exposure

Treatment time: time from surgical exposure to eruption/bonding a bracket · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure led to lower treatment time: time from surgical exposure to eruption/bonding a… compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Exposure vs no exposure to the smell and taste of milk with tube feeds

Necrotising Enterocolitis ≥ Bell's stage 2 during initial hospital stay · preterm infants

Exposure showed no clear difference in necrotising enterocolitis during hospitalisation (Bell's stage ≥ 2) compared with no exposure to the smell and taste of milk with tube feeds (low certainty).

1 finding from 1 review

Exposure vs no exposure to the smell and taste of milk with tube feeds

Late infection during hospitalisation (bacterial or fungal infection confirmed by presence of blood or CSF infection, with initiation of symptoms > 48 hours after birth) · preterm infants

Exposure showed no clear difference in late infection during hospitalisation (bacterial or fungal infection… compared with no exposure to the smell and taste of milk with tube feeds (moderate certainty).

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Gum health: midbuccal gingival recession (mm) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in gum health: midbuccal gingival recession (mm) compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Probing pocket depth · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in gum health: periodontal probing depth compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Complications or adverse effects · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)
1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Pain intensity (0‐10cm visual analogue scale) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in patient response: pain/soreness score (visual analogue scale 1 to 10) compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Discomfort/pain · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)
1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Aesthetics: canine rated as abnormal position in the dental arch · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in aesthetics: canine rated as abnormal position in the dental arch compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Gum health: bleeding on probing (Papilla Bleeding Index) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in gum health: bleeding on probing (Papilla Bleeding Index) compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Gum health: gingival recession (six-point probing) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in gum health: gingival recession (six-point probing) compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Patient response: total discomfort score (pain, difficulty eating, brushing, speaking, bad taste) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in patient response: total discomfort score (pain, difficulty eating,… compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Aesthetics: canine rated as abnormal tooth inclination · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in aesthetics: canine rated as abnormal tooth inclination compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Patient response: moderate or severe pain at 1 day postoperative · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in patient response: moderate or severe pain at 1 day postoperative compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review

Open surgical exposure vs Closed surgical exposure

Treatment time: duration of orthodontic treatment (placement to removal of fixed appliances) · People with maxillary palatally displaced (impacted) canines, unilateral or bilateral (children/adolescents; mean ages 14.2 to 17.5 years)

Open surgical exposure showed no clear difference in treatment time: duration of orthodontic treatment (placement to… compared with closed surgical exposure; GRADE not reported.

1 finding from 1 review