Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews · Emergency and Critical Care

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 2 · 33.3%Low 1 · 16.7%Moderate 1 · 16.7%High 2 · 33.3%

Total mortalitya · hypotensive shock

Epinephrine showed no clear difference in total mortalitya compared with norepinephrine (low certainty).

1 finding from 1 review

Vasopressors for hypotensive shock 2016 · Cochrane Headline outcomes only
RR 0.88 [0.63, 1.25]
1 study · 269 participants
Low

Total mortalitya · hypotensive shock

Dopamine showed no clear difference in total mortalitya compared with norepinephrine (high certainty).

1 finding from 1 review

Vasopressors for hypotensive shock 2016 · Cochrane Headline outcomes only
RR 1.07 [0.99, 1.16]
6 studies · 1400 participants
High

Arrhythmias · hypotensive shock

Dopamine leads to higher arrhythmia < BR/> compared with norepinephrine (high certainty).

1 finding from 1 review

Vasopressors for hypotensive shock 2016 · Cochrane Headline outcomes only
RR 2.33 [1.45, 3.85]
2 studies · 1931 participants
High

Total mortalitya · hypotensive shock

It is very uncertain whether terlipressin changes total mortalitya compared with norepinephrine (very low certainty).

1 finding from 1 review

Vasopressors for hypotensive shock 2016 · Cochrane Headline outcomes only
RR 0.93 [0.69, 1.26]
7 studies · 231 participants
Very low

Total mortalitya · hypotensive shock

Vasopressin showed no clear difference in total mortalitya compared with norepinephrine (moderate certainty).

1 finding from 1 review

Vasopressors for hypotensive shock 2016 · Cochrane Headline outcomes only
RR 0.9 [0.78, 1.03]
8 studies · 1108 participants
Moderate

Total mortalitya · hypotensive shock

It is very uncertain whether phenylephrine changes total mortalitya compared with norepinephrine (very low certainty).

1 finding from 1 review

Vasopressors for hypotensive shock 2016 · Cochrane Headline outcomes only
RR 1.08 [0.76, 1.55]
2 studies · 86 participants
Very low