Findings

What do systematic reviews say?

9 questions · 10 findings · 2 reviews · Gynaecological, Neuro-oncology and Orphan Cancer

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 3 · 30%Low 0 · 0%Moderate 5 · 50%High 2 · 20%

Length of Survival · people with advanced cancer with inoperable malignant bowel obstruction (MBO)

1 finding from 1 review

Home parenteral nutrition for people with inoperable malignant bowel obstruction 2018 · Cochrane Headline outcomes only
no estimate extracted
13 studies · 721 participants
Very low

Quality of life · people with advanced cancer with inoperable malignant bowel obstruction (MBO)

1 finding from 1 review

Home parenteral nutrition for people with inoperable malignant bowel obstruction 2018 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 188 participants
Very low

Adverse events · people with advanced cancer with inoperable malignant bowel obstruction (MBO)

1 finding from 1 review

Home parenteral nutrition for people with inoperable malignant bowel obstruction 2018 · Cochrane Headline outcomes only
no estimate extracted
9 studies · 280 participants
Very low

All‐cause mortality

Heparin prophylaxis showed no clear difference in mortality compared with no prophylaxis (moderate certainty).

2 findings from 1 review

Parenteral anticoagulation in ambulatory patients with cancer 2017 · Cochrane Headline outcomes only
RR 0.98 [0.93, 1.03]
18 studies · 9575 participants
Moderate
Parenteral anticoagulation in ambulatory patients with cancer 2017 · Cochrane Headline outcomes only
RR 0.99 [0.96, 1.01]
14 studies · 5229 participants
Moderate

Symptomatic VTE

Heparin prophylaxis leads to lower symptomatic VTE compared with no prophylaxis (high certainty).

1 finding from 1 review

Parenteral anticoagulation in ambulatory patients with cancer 2017 · Cochrane Headline outcomes only
RR 0.56 [0.47, 0.68]
16 studies · 9036 participants
High

Major bleeding

Heparin prophylaxis showed no clear difference in major bleeding compared with no prophylaxis (moderate certainty).

1 finding from 1 review

Parenteral anticoagulation in ambulatory patients with cancer 2017 · Cochrane Headline outcomes only
RR 1.3 [0.94, 1.79]
18 studies · 9592 participants
Moderate

Minor bleeding

Heparin prophylaxis leads to higher minor bleeding compared with no prophylaxis (high certainty).

1 finding from 1 review

Parenteral anticoagulation in ambulatory patients with cancer 2017 · Cochrane Headline outcomes only
RR 1.7 [1.13, 2.55]
16 studies · 9245 participants
High

Thrombocytopenia

Heparin prophylaxis showed no clear difference in thrombocytopenia compared with no prophylaxis (moderate certainty).

1 finding from 1 review

Parenteral anticoagulation in ambulatory patients with cancer 2017 · Cochrane Headline outcomes only
RR 0.69 [0.37, 1.27]
12 studies · 5832 participants
Moderate

Quality of life impairment

1 finding from 1 review

Parenteral anticoagulation in ambulatory patients with cancer 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 2241 participants
Moderate