Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

29 questions · 29 findings · 2 reviews · Colorectal · Headline outcomes only

No studies found 1 · 3.4%GRADE not reported 3 · 10.3%Very low 9 · 31%Low 16 · 55.2%Moderate 0 · 0%High 0 · 0%

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Wound infection · lower gastrointestinal surgery

It is very uncertain whether early enteral nutrition within 24 hours of lower gastrointestinal… changes wound infection compared with later commencement (very low certainty).

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Intraabdominal abscess · lower gastrointestinal surgery

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in intraabdominal abscess compared with later commencement (low certainty).

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Anastomotic leakage/dehiscence · lower gastrointestinal surgery

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in anastomotic leakage/dehiscence compared with later commencement (low certainty).

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Pneumonia · lower gastrointestinal surgery

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in pneumonia (within hospital stay) compared with later commencement (low certainty).

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

All‐cause mortality · lower gastrointestinal surgery

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in mortality compared with later commencement (low certainty).

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Vomiting · lower gastrointestinal surgery

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in vomiting compared with later commencement (low certainty).

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Nausea · lower gastrointestinal surgery

Early enteral nutrition within 24 hours of lower gastrointestinal… showed no clear difference in nausea compared with later commencement (low certainty).

1 finding from 1 review

Early enteral nutrition within 24 hours of lower gastrointestinal surgery vs later commencement

Nausea and vomiting · lower gastrointestinal surgery

It is very uncertain whether early enteral nutrition within 24 hours of lower gastrointestinal… changes nausea and vomiting compared with later commencement (very low certainty).

1 finding from 1 review

Immune‐enhancing supplements (oral or enteral) vs usual care or control

Infectious complications · people undergoing gastrointestinal surgery

Immune‐enhancing supplements (oral or enteral) showed no clear difference in infectious complications recorded up to 30 days postdischarge compared with usual care or control (low certainty).

1 finding from 1 review

Immune‐enhancing supplements (oral or enteral) vs usual care or control

Non‐infectious complications · people undergoing gastrointestinal surgery

Immune‐enhancing supplements (oral or enteral) showed no clear difference in non‐ infectious complications recorded up to 30 days postdischarge compared with usual care or control (low certainty).

1 finding from 1 review

Preoperative enteral nutrition (standard formula) vs usual care or control

Infectious complications · people undergoing gastrointestinal surgery

It is very uncertain whether preoperative enteral nutrition (standard formula) changes infectious complications compared with usual care or control (very low certainty).

1 finding from 1 review