Findings

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Evidence found and GRADE certainty

42 questions · 51 findings · 3 reviews · Orthodontics

No studies found 10 · 19.6%GRADE not reported 19 · 37.3%Very low 8 · 15.7%Low 12 · 23.5%Moderate 2 · 3.9%High 0 · 0%

Early treatment (two-phase) with headgear vs Early treatment (two-phase) with functional appliance

Incidence of incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear showed no clear difference in incidence of incisal trauma compared with early treatment (two-phase) with functional appliance; GRADE not reported.

2 findings from 1 review

Early treatment (two-phase) with headgear vs Early treatment (two-phase) with functional appliance

Final ANB · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear showed no clear difference in final ANB compared with early treatment (two-phase) with functional appliance; GRADE not reported.

2 findings from 1 review

Early treatment (two-phase) with headgear vs Early treatment (two-phase) with functional appliance

PAR score · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear showed no clear difference in PAR score compared with early treatment (two-phase) with functional appliance; GRADE not reported.

1 finding from 1 review

Early treatment (two-phase) with headgear vs Early treatment (two-phase) with functional appliance

Final overjet · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear showed no clear difference in final overjet compared with early treatment (two-phase) with functional appliance; GRADE not reported.

2 findings from 1 review

Early loading of mini-screw implant vs Delayed loading of mini-screw implant

Success of the anchorage device · Patients undergoing orthodontic treatment requiring surgical (mini-screw implant) anchorage

Early loading of mini-screw implant showed no clear difference in success of the anchorage device compared with delayed loading of mini-screw implant; GRADE not reported.

1 finding from 1 review

Early treatment (two-phase) with headgear vs Late treatment (one-phase in adolescence) with headgear

PAR score · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear showed no clear difference in PAR score compared with late treatment (one-phase in adolescence) with headgear; GRADE not reported.

1 finding from 1 review

Early treatment (two-phase) with headgear vs Late treatment (one-phase in adolescence) with headgear

Incidence of new incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear may leads to lower incidence of new incisal trauma compared with late treatment (one-phase in adolescence) with headgear (low certainty).

1 finding from 1 review

Early treatment (two-phase) with headgear vs Late treatment (one-phase in adolescence) with headgear

Final overjet · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear showed no clear difference in final overjet compared with late treatment (one-phase in adolescence) with headgear (low certainty).

2 findings from 1 review

Early treatment (two-phase) with headgear vs Late treatment (one-phase in adolescence) with headgear

Incidence of incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear showed no clear difference in incidence of incisal trauma compared with late treatment (one-phase in adolescence) with headgear; GRADE not reported.

1 finding from 1 review

Early treatment (two-phase) with headgear vs Late treatment (one-phase in adolescence) with headgear

Final ANB · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase) with headgear led to lower final ANB compared with late treatment (one-phase in adolescence) with headgear; GRADE not reported.

2 findings from 1 review

Early treatment (two-phase: phase 1 in childhood, phase 2 in adolescence) with functional appliance vs Late treatment (one-phase in adolescence) with functional appliance

Self concept · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase: phase 1 in childhood, phase 2 in… showed no clear difference in self concept compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.

2 findings from 1 review

Early treatment (two-phase: phase 1 in childhood, phase 2 in adolescence) with functional appliance vs Late treatment (one-phase in adolescence) with functional appliance

Incidence of new incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase: phase 1 in childhood, phase 2 in… probably leads to lower incidence of new incisal trauma compared with late treatment (one-phase in adolescence) with functional appliance (moderate certainty).

1 finding from 1 review

Early treatment (two-phase: phase 1 in childhood, phase 2 in adolescence) with functional appliance vs Late treatment (one-phase in adolescence) with functional appliance

Final overjet · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower final overjet compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.

2 findings from 1 review

Early treatment (two-phase: phase 1 in childhood, phase 2 in adolescence) with functional appliance vs Late treatment (one-phase in adolescence) with functional appliance

Final ANB · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower final ANB compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.

2 findings from 1 review

Early treatment (two-phase: phase 1 in childhood, phase 2 in adolescence) with functional appliance vs Late treatment (one-phase in adolescence) with functional appliance

Incidence of incisal trauma · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase: phase 1 in childhood, phase 2 in… showed no clear difference in incidence of incisal trauma compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.

1 finding from 1 review

Early treatment (two-phase: phase 1 in childhood, phase 2 in adolescence) with functional appliance vs Late treatment (one-phase in adolescence) with functional appliance

PAR score · Children (7 to 11 years) and adolescents (12 to 16 years) with prominent upper front teeth (Class II malocclusion)

Early treatment (two-phase: phase 1 in childhood, phase 2 in… led to lower PAR score compared with late treatment (one-phase in adolescence) with functional appliance; GRADE not reported.

2 findings from 1 review

12,500 ppm F (NaF/olaflur/dectaflur) amine fluoride gel vs Placebo gel

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

Patient-used 5000 ppm F toothpaste, daily vs 1450 to 1500 ppm F toothpaste

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily

Number of participants with more severe DLs (severity of DLs) · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review

1400/250 ppm F (amine F/SnF2) toothpaste + mouthrinse, daily vs 1400/250 ppm F (NaF) toothpaste + mouthrinse, daily

Adverse effects · Orthodontic patients of any age with fixed braces (new DLs assessed at debond)

The review found no eligible studies for this question.

1 finding from 1 review