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Evidence found and GRADE certainty

62 questions · 62 findings · 6 reviews · Neonatal · Headline outcomes only

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No studies found 16 · 25.8%GRADE not reported 0 · 0%Very low 9 · 14.5%Low 26 · 41.9%Moderate 10 · 16.1%High 1 · 1.6%

Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone

Number of infants with feed interruption episodes (lasting ≥ 12 hours) · feed interruption while monitoring gastric residual

It is very uncertain whether summary of findings table ‐ Quality and volume of gastric residual changes number of infants with feed interruption episodes (lasting ≥ 12 hours) compared with quality of gastric residual alone (very low certainty).

1 finding from 1 review

Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone

Risk of invasive Infection · feed interruption while monitoring gastric residual

Summary of findings table ‐ Quality and volume of gastric residual showed no clear difference in risk of invasive Infection compared with quality of gastric residual alone (low certainty).

1 finding from 1 review

Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone

Mortality before hospital discharge · feed interruption while monitoring gastric residual

Summary of findings table ‐ Quality and volume of gastric residual showed no clear difference in all‐cause mortality before hospital discharge compared with quality of gastric residual alone (low certainty).

1 finding from 1 review

Summary of findings table ‐ Quality and volume of gastric residual vs quality of gastric residual alone

Risk of necrotising enterocolitis stage ≥ 2 · feed interruption while monitoring gastric residual

Summary of findings table ‐ Quality and volume of gastric residual showed no clear difference in risk of necrotising enterocolitis stage ≥ 2 compared with quality of gastric residual alone (low certainty).

1 finding from 1 review

Targeted individualized vs standard non‐individualized fortification

In‐hospital mortality · promoting growth and development in very low birth weight infants receiving human milk

It is very uncertain whether targeted individualized changes in‐hospital mortality compared with standard non‐individualized fortification (very low certainty).

1 finding from 1 review

Targeted individualized vs standard non‐individualized fortification

Necrotising enterocolitis · promoting growth and development in very low birth weight infants receiving human milk

It is very uncertain whether targeted individualized changes necrotizing enterocolitis compared with standard non‐individualized fortification (very low certainty).

1 finding from 1 review

Targeted individualized vs standard non‐individualized fortification

Culture‐proven late‐onset bacterial sepsis · promoting growth and development in very low birth weight infants receiving human milk

It is very uncertain whether targeted individualized changes culture‐proven late‐onset bacterial sepsis compared with standard non‐individualized fortification (very low certainty).

1 finding from 1 review