Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

80 questions · 80 findings · 6 reviews · Infectious Diseases · Headline outcomes only

No studies found 1 · 1.3%GRADE not reported 5 · 6.3%Very low 20 · 25%Low 24 · 30%Moderate 21 · 26.3%High 9 · 11.3%

Pyrethroid‐like indoor residual spraying (IRS) + insecticide‐treated nets (ITNs) vs ITNs alone

Malaria incidence · people at risk of malaria

Pyrethroid‐like indoor residual spraying (IRS) + insecticide‐treated… showed no clear difference in malaria incidence compared with ITNs alone (moderate certainty).

1 finding from 1 review

Pyrethroid‐like indoor residual spraying (IRS) + insecticide‐treated nets (ITNs) vs ITNs alone

Malaria parasite prevalence · people at risk of malaria

Pyrethroid‐like indoor residual spraying (IRS) + insecticide‐treated… showed no clear difference in malaria parasite prevalence compared with ITNs alone (moderate certainty).

1 finding from 1 review

Pyrethroid‐like indoor residual spraying (IRS) + insecticide‐treated nets (ITNs) vs ITNs alone

Anaemia prevalence (haemoglobin < 8 g/dL) · people at risk of malaria

Pyrethroid‐like indoor residual spraying (IRS) + insecticide‐treated… showed no clear difference in anaemia prevalence (haemoglobin < 8 g/dL) compared with ITNs alone (low certainty).

1 finding from 1 review

Non‐pyrethroid‐like indoor residual spraying (IRS) plus insecticide‐treated nets (ITNs) vs ITNs alone

Malaria incidence · people at risk of malaria

Non‐pyrethroid‐like indoor residual spraying (IRS) plus… showed no clear difference in malaria incidence compared with ITNs alone (low certainty).

1 finding from 1 review

Non‐pyrethroid‐like indoor residual spraying (IRS) plus insecticide‐treated nets (ITNs) vs ITNs alone

Malaria parasite prevalence · people at risk of malaria

Non‐pyrethroid‐like indoor residual spraying (IRS) plus… leads to lower malaria parasite prevalence compared with ITNs alone (high certainty).

1 finding from 1 review

Non‐pyrethroid‐like indoor residual spraying (IRS) plus insecticide‐treated nets (ITNs) vs ITNs alone

Anaemia prevalence · people at risk of malaria

Non‐pyrethroid‐like indoor residual spraying (IRS) plus… showed no clear difference in anaemia prevalence compared with ITNs alone (low certainty).

1 finding from 1 review

Intervention not reported

Residual pleural fluid on chest X‐ray at 8 weeks · adults and adolescents with pleural TB

The intervention may leads to lower residual pleural fluid on chest X‐ray at 8 weeks (low certainty).

1 finding from 1 review

Intervention not reported

Residual pleural fluid on chest X‐ray at 24 weeks · adults and adolescents with pleural TB

The intervention may leads to lower residual pleural fluid on chest X‐ray at 24 weeks (low certainty).

1 finding from 1 review