Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

18 questions · 18 findings · 4 reviews · Skin · Headline outcomes only

No studies found 6 · 33.3%GRADE not reported 1 · 5.6%Very low 1 · 5.6%Low 5 · 27.8%Moderate 5 · 27.8%High 0 · 0%

Intervention not reported

Severe skin drug‐induced rash · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Hospitalisation for drug‐induced skin reaction · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The review found no eligible studies for this question.

1 finding from 1 review

Chinese herbal medicines vs drugs

Total effectiveness rate with subgroup analysis ‐ individualised treatment Clinician's rating · atopic eczema

CHM may leads to higher total effectiveness rate with subgroup analysis ‐ individualised… compared with drugs (low certainty).

1 finding from 1 review

Chinese herbal medicines vs drugs

Total effectiveness rate with subgroup analysis ‐ non‐individualised treatment Clinician's rating · atopic eczema

It is very uncertain whether CHM changes total effectiveness rate with subgroup analysis ‐ non‐individualised… compared with drugs (very low certainty).

1 finding from 1 review

Intervention not reported

Long‐term sequelae · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

SJS/TEN (Stevens‐Johnson syndrome/toxic epidermal necrolysis) · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

AGEP (acute generalised exanthematous pustulosis) · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

HSS (hypersensitivity) reaction including SJS/TEN (clinically diagnosed) (6 weeks clinical assessment) · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The intervention probably leads to lower HSS (hypersensitivity) reaction including SJS/TEN (clinically… (moderate certainty).

1 finding from 1 review

Intervention not reported

HSS reaction including SJS/TEN (immunologically confirmed) (6 weeks clinical assessment) · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The intervention probably leads to lower HSS reaction including SJS/TEN (immunologically confirmed) (6 weeks… (moderate certainty).

1 finding from 1 review

Intervention not reported

Death · patients with HIV‐1 infection and a pre‐established clinical need for treatment with an antiretroviral drug regimen containing abacavir…

The review found no eligible studies for this question.

1 finding from 1 review