Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

17 questions · 17 findings · 5 reviews · Gynaecology and Fertility · Headline outcomes only

No studies found 4 · 23.5%GRADE not reported 0 · 0%Very low 6 · 35.3%Low 4 · 23.5%Moderate 3 · 17.6%High 0 · 0%

Metformin vs placebo or no treatment

Gastrointestinal adverse events · Women with polycystic ovary syndrome, oligo amenorrhoea and subfertility

Metformin probably leads to higher adverse events (gastrointestinal) per woman compared with placebo or no treatment (moderate certainty).

1 finding from 1 review

Metformin vs placebo or no treatment

Clinical pregnancy rate · Women with polycystic ovary syndrome, oligo amenorrhoea and subfertility

Metformin probably leads to higher clinical pregnancy rate per woman compared with placebo or no treatment (moderate certainty).

1 finding from 1 review