What do systematic reviews say?

Intervention not reported

It is very uncertain whether the intervention changes improvement in visual impairment at 6 months (very low certainty).

• Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis 2016 · Cochrane Headline outcomes only
  RR 1.06 [0.8, 1.39]
  1 study · 240 participants
  Very low

Intervention not reported

• Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intervention not reported

• Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  Studies not reported
  Very low

Intervention not reported

It is very uncertain whether the intervention changes clinical outcomes: improvement in iridocyclitis at 6 months (very low certainty).

• Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis 2016 · Cochrane Headline outcomes only
  RR 1.24 [0.69, 2.22]
  1 study · 240 participants
  Very low

Intervention not reported

It is very uncertain whether the intervention changes clinical outcomes: improvement in punctate keratitis at 6 months (very low certainty).

• Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis 2016 · Cochrane Headline outcomes only
  RR 1.43 [1.02, 2]
  1 study · 240 participants
  Very low

Intervention not reported

The intervention probably leads to lower adverse events (moderate certainty).

• Doxycycline plus ivermectin versus ivermectin alone for treatment of patients with onchocerciasis 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2010 participants
  Moderate