What do systematic reviews say?

Povidone iodine coolant vs Distilled water coolant

It is very uncertain whether povidone iodine coolant changes reduction in level of contamination in aerosols (CFU): povidone… compared with distilled water coolant (very low certainty).

• Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious diseases 2020 · Cochrane All outcomes
  MD -656.45 [-672.74, -640.16]
  1 study · 40 participants
  Very low

Cinnamon extract coolant vs Distilled water coolant

It is very uncertain whether cinnamon extract coolant changes reduction in level of contamination in aerosols (CFU): cinnamon… compared with distilled water coolant (very low certainty).

• Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious diseases 2020 · Cochrane All outcomes
  MD -644.55 [-668.70, -620.40]
  1 study · 40 participants
  Very low

Antimicrobial coolant A (chlorhexidine) vs Distilled water coolant

It is very uncertain whether chlorhexidine coolant changes reduction in level of contamination in aerosols (CFU): chlorhexidine… compared with distilled water coolant (very low certainty).

• Interventions to reduce contaminated aerosols produced during dental procedures for preventing infectious diseases 2020 · Cochrane All outcomes
  MD -124.00 [-135.78, -112.22]
  1 study · 20 participants
  Very low

Chlorhexidine vs Water (distilled)

• Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare… 2022 · Cochrane All outcomes

  operator level
  At operator level, because of high heterogeneity (I2 = 98%), the results were not meta-analysed (6 studies, 196 participants). No pooled estimate or GRADE rating.
  6 studies · 196 participants
  GRADE not reported
• Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare… 2022 · Cochrane All outcomes

  combined patient and operator level
  MD -632.94 [-1267.33, 1.45]
  3 studies · 80 participants
  Very low
• Preprocedural mouth rinses for preventing transmission of infectious diseases through aerosols in dental healthcare… 2022 · Cochrane All outcomes

  tempered CHX; combined operator, assistant and patient level
  MD -101.1 [-107.01, -95.19]
  1 study · 20 participants
  Low