Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

80 questions · 92 findings · 5 reviews

No studies found 14 · 15.2%GRADE not reported 4 · 4.3%Very low 22 · 23.9%Low 45 · 48.9%Moderate 4 · 4.3%High 3 · 3.3%

Dietary supplements vs placebo

Dill seed versus placebo Pain score · women with moderate or severe primary dysmenorrhoea
11 findings from 1 review
Show 8 more findings

Dietary supplements vs placebo

Relief of pain · women with moderate or severe primary dysmenorrhoea

Dietary supplements may leads to higher zataria versus placebo Pain relief compared with placebo (low certainty).

3 findings from 1 review

Dietary supplements vs placebo

Zinc sulphate versus placebo Adverse effects · women with moderate or severe primary dysmenorrhoea

It is very uncertain whether dietary supplements changes zinc sulphate versus placebo Adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements vs placebo

Ginger versus placebo Adverse effects · women with moderate or severe primary dysmenorrhoea

It is very uncertain whether dietary supplements changes ginger versus placebo Adverse effects compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (lycopene) vs placebo

Relief of burning/discomfort (symptom relief; pain intensity) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms
1 finding from 1 review
  • Interventions for treating burning mouth syndrome 2016 · Cochrane All outcomes
    short-term (up to 3 months) · lycopene
    Lycopene (Cano-Carrillo 2014) contributes to the dietary supplements short-term symptom-relief comparison (12 RCTs, insufficient/contradictory); no separate lycopene symptom-relief estimate reported.
    1 study · 50 participants
    GRADE not reported

Dietary supplements (lycopene) vs placebo

Change in QoL - depression (surrogate marker) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (lycopene) changes change in QoL - depression (surrogate marker) compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (lycopene) vs placebo

QoL · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (lycopene) changes change in quality of life (QoL) compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (lycopene) vs placebo

Change in QoL - anxiety (surrogate marker) · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (lycopene) changes change in QoL - anxiety (surrogate marker) compared with placebo (very low certainty).

1 finding from 1 review

Alpha‐lipoic acid vs placebo

Change in feeling of dryness · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Alpha‐lipoic acid vs placebo

Change in taste · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

The review found no eligible studies for this question.

1 finding from 1 review

Dietary supplements (Catuama herbal compound) vs placebo

Adverse effects: exacerbation of symptoms · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (Catuama herbal compound) changes adverse effects: exacerbation of symptoms compared with placebo (very low certainty).

1 finding from 1 review

Dietary supplements (Catuama herbal compound) vs placebo

Somnolence · People with primary burning mouth syndrome (BMS), that is, oral mucosal pain with no dental or medical cause for such symptoms

It is very uncertain whether dietary supplements (Catuama herbal compound) changes adverse effects: drowsiness compared with placebo (very low certainty).

1 finding from 1 review