Findings

What do systematic reviews say?

11 questions · 11 findings · 2 reviews

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No studies found 4 · 36.4%GRADE not reported 0 · 0%Very low 3 · 27.3%Low 4 · 36.4%Moderate 0 · 0%High 0 · 0%

Desipramine (antidepressant) vs placebo

Adverse events · adults with antisocial personality disorder

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desipramine (antidepressant) vs placebo

Aggression · adults with antisocial personality disorder

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desipramine (antidepressant) vs placebo

Reconviction · adults with antisocial personality disorder

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desipramine (antidepressant) vs placebo

Global state/functioning · adults with antisocial personality disorder

The review found no eligible studies for this question.

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Desipramine (antidepressant) vs placebo

Social functioning · adults with antisocial personality disorder

1 finding from 1 review

Pharmacological interventions for antisocial personality disorder 2020 · Cochrane Headline outcomes only
no estimate extracted
1 study · 29 participants
Very low

Tricyclic antidepressants vs placebo

Efficacy for ADHD symptoms (parents using a rating scale) ‐ desipramine · Children and adolescents with ADHD

1 finding from 1 review

Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 99 participants
Low

Tricyclic antidepressants vs placebo

Efficacy for ADHD symptoms (teachers using a rating scale) ‐ desipramine · Children and adolescents with ADHD

1 finding from 1 review

Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 89 participants
Low

Tricyclic antidepressants vs placebo

CGI (response rate) ‐ desipramine and nortriptyline · Children and adolescents with ADHD

Tricyclic antidepressants (TCAs) may leads to higher CGI (response rate) ‐ desipramine and nortriptyline compared with placebo (low certainty).

1 finding from 1 review

Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents 2014 · Cochrane Headline outcomes only
OR 18.5 [6.29, 54.39]
3 studies · 125 participants
Low

Tricyclic antidepressants vs placebo

Clinical global impression (response rate) ‐ desipramine · Children and adolescents with ADHD

Tricyclic antidepressants (TCAs) may leads to higher clinical global impression (response rate) ‐ desipramine compared with placebo (low certainty).

1 finding from 1 review

Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents 2014 · Cochrane Headline outcomes only
OR 26.41 [7.41, 94.18]
2 studies · 103 participants
Low

Tricyclic antidepressants vs placebo

All‐cause treatment discontinuation ‐ desipramine · Children and adolescents with ADHD

1 finding from 1 review

Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 134 participants
Very low

Desipramine (antidepressant) vs clonidine

ADHD symptoms · Children and adolescents with ADHD

1 finding from 1 review

Tricyclic antidepressants for attention deficit hyperactivity disorder (ADHD) in children and adolescents 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 68 participants
Very low