Findings

What do systematic reviews say?

49 questions · 50 findings · 2 reviews

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No studies found 0 · 0%GRADE not reported 1 · 2%Very low 15 · 30%Low 19 · 38%Moderate 10 · 20%High 5 · 10%

Closest answers

The findings closest to your search, judged one by one by TypeSafe's Jev model.

Direct match · question page
- Deep brain stimulation vs sham stimulation · Dystonia‐specific improvement
  Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 40 participants
  Low
Direct match · question page
- Deep brain stimulation vs sham stimulation · Subjective Evaluation of Clinical Status
  Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 37 participants
  Low
Direct match · question page
- Deep brain stimulation vs sham stimulation · Clinical status(
  Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 62 participants
  Low
Direct match · question page
- Deep brain stimulation vs sham stimulation · Dystonia‐specific symptoms (
  Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 62 participants
  Low
Direct match
- · Seizure frequency reduction (1‐ to 3‐month blinded evaluation period)
  Deep brain and cortical stimulation for epilepsy 2017 · Cochrane Headline outcomes only
  no estimate extracted
  3 studies · 19 participants
  Low

Deep brain stimulation vs sham stimulation

Dystonia‐specific improvement · adults with generalised or segmental dystonia

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 40 participants
Low

Deep brain stimulation vs sham stimulation

Health‐related quality of life (mental) · adults with cervical dystonia

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Very low

Deep brain stimulation vs sham stimulation

Functional capacity · adults with cervical dystonia

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Very low

Deep brain stimulation vs sham stimulation

Emotional Assessment · adults with cervical dystonia

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Low

Deep brain stimulation vs sham stimulation

Adverse events · adults with dystonia (generalised, segmental, and cervical)

It is very uncertain whether deep brain stimulation changes adverse Events compared with sham stimulation (very low certainty).

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
RR 1.58 [0.98, 2.54]
2 studies · 102 participants
Very low

Deep brain stimulation vs sham stimulation

Tolerability · adults with dystonia (generalised, segmental, and cervical)

It is very uncertain whether deep brain stimulation changes tolerability compared with sham stimulation (very low certainty).

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
RR 1.86 [0.16, 21.57]
2 studies · 102 participants
Very low

Deep brain stimulation vs sham stimulation

Subjective Evaluation of Clinical Status · adults with generalised or segmental dystonia

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 37 participants
Low

Deep brain stimulation vs sham stimulation

Quality of Life Assessment · adults with generalised or segmental dystonia

2 findings from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Low
Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 33 participants
Very low

Deep brain stimulation vs sham stimulation

Functional capacity · adults with generalised or segmental dystonia

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 39 participants
Low

Deep brain stimulation vs sham stimulation

Emotional Assessment · adults with generalised or segmental dystonia

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 30 participants
Very low

Deep brain stimulation vs sham stimulation

Dystonia‐specific symptoms ( · adults with cervical dystonia

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Low

Deep brain stimulation vs sham stimulation

Clinical status( · adults with cervical dystonia

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Low

Deep brain stimulation vs sham stimulation

Physical functioning component of health‐related quality of life, measured using various scales · adults with cervical dystonia

1 finding from 1 review

Deep brain stimulation for dystonia 2019 · Cochrane Headline outcomes only
no estimate extracted
1 study · 62 participants
Very low

Intervention not reported

Seizure freedom (3‐month blinded evaluation period) · adults with IQ > 70 with refractory focal epilepsy

The intervention showed no clear difference in seizure freedom (3‐month blinded evaluation period) (moderate certainty).

1 finding from 1 review

Deep brain and cortical stimulation for epilepsy 2017 · Cochrane Headline outcomes only
OR 0.33 [0.01, 8.36]
1 study · 109 participants
Moderate

Intervention not reported

Adverse events · patients with refractory (multi)focal or generalized epilepsy

1 finding from 1 review

Deep brain and cortical stimulation for epilepsy 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 19 participants
Low

Intervention not reported

Neuropsychological outcome (3 months) · patients with refractory (multi)focal or generalized epilepsy

1 finding from 1 review

Deep brain and cortical stimulation for epilepsy 2017 · Cochrane Headline outcomes only
no estimate extracted
1 study · 6 participants
Very low

Intervention not reported

Quality of life · patients with refractory (multi)focal or generalized epilepsy

1 finding from 1 review

Deep brain and cortical stimulation for epilepsy 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported

Intervention not reported

Seizure freedom (1‐ to 3‐month blinded evaluation period) · patients with refractory (multi)focal or generalized epilepsy

The intervention showed no clear difference in seizure freedom (1‐ to 3‐month blinded evaluation period) (moderate certainty).

1 finding from 1 review

Deep brain and cortical stimulation for epilepsy 2017 · Cochrane Headline outcomes only
OR 0.96 [0.22, 4.12]
3 studies · 22 participants
Moderate

Intervention not reported

Responder rate (1‐ to 3‐month blinded evaluation period) · patients with refractory (multi)focal or generalized epilepsy

The intervention showed no clear difference in responder rate (1‐ to 3‐month blinded evaluation period) (low certainty).

1 finding from 1 review

Deep brain and cortical stimulation for epilepsy 2017 · Cochrane Headline outcomes only
OR 2.43 [0.46, 12.84]
3 studies · 19 participants
Low

Intervention not reported

Seizure frequency reduction (1‐ to 3‐month blinded evaluation period) · patients with refractory (multi)focal or generalized epilepsy

1 finding from 1 review

Deep brain and cortical stimulation for epilepsy 2017 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 19 participants
Low