Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

160 questions · 160 findings · 28 reviews · Vascular · Headline outcomes only

No studies found 17 · 10.6%GRADE not reported 7 · 4.4%Very low 38 · 23.8%Low 56 · 35%Moderate 36 · 22.5%High 6 · 3.8%

Intervention not reported

30‐Day amputation‐free survival · patients with less than 42 days' lower limb ischaemia
1 finding from 1 review

Intervention not reported

30‐Day mortality · patients with less than 42 days' lower limb ischaemia
1 finding from 1 review

Effects of clinically‐indicated replacement vs routine change of peripheral intravenous catheters

Thrombophlebitis (per device days) (during hospitalisation) · any patient requiring a PIVC expected to remain in‐situ for at least 3 days

Effects of clinically‐indicated replacement showed no clear difference in thrombophlebitis (per device days) (during hospitalisation) compared with routine change of peripheral intravenous catheters (moderate certainty).

1 finding from 1 review

Intervention not reported

Death from bleeding complications (up to 30 days · vascular surgery patients who undergo creation of an anastomosis

The review found no eligible studies for this question.

1 finding from 1 review

Intervention not reported

Postoperative bleeding (up to 30 days · vascular surgery patients who undergo creation of an anastomosis

The intervention showed no clear difference in postoperative bleeding (up to 30 days (low certainty).

1 finding from 1 review

Intervention not reported

Unplanned return to the operating room (up to 30 days · vascular surgery patients who undergo creation of an anastomosis

The intervention showed no clear difference in unplanned return to the operating room (up to 30 days (low certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Short‐term mortality (30‐day or in‐hospital) · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in short‐term mortality (30‐day or in‐hospital) compared with cut‐down femoral artery access (low certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Wound infection · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in wound infection (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Major complications · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in major complications (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review

Totally percutaneous vs cut‐down femoral artery access

Bleeding complications (30‐day or in‐hospital) · people undergoing elective bifurcated abdominal endovascular aneurysm repair

Totally percutaneous showed no clear difference in bleeding complications (30‐day or in‐hospital) compared with cut‐down femoral artery access (moderate certainty).

1 finding from 1 review

Tranexamic acid vs placebo

Risk of reoperation or repeat procedure for bleeding within 7 days · people aged 18 and over undergoing vascular surgery

It is very uncertain whether summary of findings: Tranexamic acid changes risk of reoperation or repeat procedure for bleeding within 7 days compared with placebo (very low certainty).

1 finding from 1 review