Honey vs placebo
Day 5 · acute cough in children
1 finding from 1 review
- no estimate extracted5 participantsGRADE not reported
Findings
What do systematic reviews say?
135 questions · 145 findings · 44 reviews · Acute Respiratory Infections · Headline outcomes only
No studies found 10 · 6.9%GRADE not reported 18 · 12.4%Very low 21 · 14.5%Low 54 · 37.2%Moderate 28 · 19.3%High 14 · 9.7%
Honey vs salbutamol
Day 5 · acute cough in children
1 finding from 1 review
- no estimate extracted5 participantsGRADE not reported
Systemic corticosteroids vs placebo
Day 5 · children with acute otitis media
1 finding from 1 review
- no estimate extracted0 studies · 0 participantsGRADE not reported
Intervention not reported
Failure to recover by day 5 (complete resolution of all symptoms) · adults with common cold
It is very uncertain whether the intervention changes failure to recover by day 5 (complete resolution of all symptoms) (very low certainty).
1 finding from 1 review
- Pelargonium sidoides extract for treating acute respiratory tract infections 2013 · Cochrane Headline outcomes onlyRR 0.96 [0.9, 1.03]1 study · 103 participantsVery low
Chest physiotherapy vs no chest physiotherapy
Length of hospital stay · children aged from 29 days to 12 years with pneumonia
Chest physiotherapy showed no clear difference in duration of hospital stay (days) ( compared with no chest physiotherapy (low certainty).
1 finding from 1 review
- MD 0.14 studies · 415 participantsLow
Zinc vs placebo
Duration of cold symptoms (days) · adults and children without colds
1 finding from 1 review
- no estimate extracted3 studies · 740 participantsModerate
Zinc vs placebo
Duration of cold symptoms (days) · adults and children with colds and/or upper respiratory infections
1 finding from 1 review
- no estimate extracted8 studies · 972 participantsLow
Immediate antibiotics vs expectant observation
Pain ‐ Pain at 11 to 14 days · children with acute otitis media
Immediate antibiotics showed no clear difference in pain ‐ Pain at 11 to 14 days compared with expectant observation (low certainty).
1 finding from 1 review
- RR 0.91 [0.75, 1.1]1 study · 247 participantsLow
Antibiotics vs placebo
Pain ‐ pain at 2 to 3 days · children with acute otitis media
Antibiotics leads to lower pain ‐ pain at 2 to 3 days compared with placebo (high certainty).
1 finding from 1 review
- RR 0.71 [0.58, 0.88]7 studies · 2320 participantsHigh
Antibiotics vs placebo
Pain ‐ pain at 4 to 7 days · children with acute otitis media
Antibiotics showed no clear difference in pain ‐ pain at 4 to 7 days compared with placebo (high certainty).
1 finding from 1 review
- RR 0.76 [0.5, 1.14]7 studies · 1264 participantsHigh
Antibiotics vs placebo
Pain ‐ pain at 10 to 12 days · children with acute otitis media
Antibiotics probably leads to lower pain ‐ pain at 10 to 12 days compared with placebo (moderate certainty).
1 finding from 1 review
- RR 0.33 [0.17, 0.66]1 study · 278 participantsModerate
Immediate antibiotics vs expectant observation
Pain ‐ pain at 2 to 3 days · children with acute otitis media
Immediate antibiotics may leads to lower pain ‐ Pain at 2 to 3 days compared with expectant observation (low certainty).
1 finding from 1 review
- RR 0.53 [0.35, 0.79]1 study · 396 participantsLow
Immediate antibiotics vs expectant observation
Pain ‐ Pain at 3 to 7 days · children with acute otitis media
Immediate antibiotics showed no clear difference in pain ‐ Pain at 3 to 7 days compared with expectant observation (moderate certainty).
1 finding from 1 review
- RR 0.75 [0.5, 1.12]4 studies · 959 participantsModerate
Nebulised hypertonic saline vs nebulised 0.9% saline
Length of hospital stay · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
- Nebulised hypertonic saline solution for acute bronchiolitis in infants 2023 · Cochrane Headline outcomes onlyno estimate extracted21 studies · 2479 participantsLow
Nebulised hypertonic saline vs nebulised 0.9% saline
Clinical severity score (post‐treatment) at day 1 · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
- Nebulised hypertonic saline solution for acute bronchiolitis in infants 2023 · Cochrane Headline outcomes onlyno estimate extracted10 studies · 893 participantsLow
Nebulised hypertonic saline vs nebulised 0.9% saline
Clinical severity score (post‐treatment) at day 2 · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
- Nebulised hypertonic saline solution for acute bronchiolitis in infants 2023 · Cochrane Headline outcomes onlyno estimate extracted10 studies · 907 participantsLow
Nebulised hypertonic saline vs nebulised 0.9% saline
Clinical severity score (post‐treatment) at day 3 · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
- Nebulised hypertonic saline solution for acute bronchiolitis in infants 2023 · Cochrane Headline outcomes onlyno estimate extracted10 studies · 785 participantsLow
Nebulised hypertonic saline vs nebulised 0.9% saline
Number of days to resolution of symptoms and signs (wheezing) · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
- Nebulised hypertonic saline solution for acute bronchiolitis in infants 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 205 participantsVery low
Nebulised hypertonic saline vs nebulised 0.9% saline
Number of days to resolution of symptoms and signs (cough) · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
- Nebulised hypertonic saline solution for acute bronchiolitis in infants 2023 · Cochrane Headline outcomes onlyno estimate extracted3 studies · 363 participantsVery low
Nebulised hypertonic saline vs nebulised 0.9% saline
Number of days to resolution of symptoms and signs(pulmonary moist crackles) · infants up to 24 months of age with acute bronchiolitis
1 finding from 1 review
- Nebulised hypertonic saline solution for acute bronchiolitis in infants 2023 · Cochrane Headline outcomes onlyno estimate extracted2 studies · 205 participantsVery low