Cochrane · systematic review · CD006323

Pelargonium sidoides extract for treating acute respiratory tract infections

Timmer, A, Günther, J, Motschall, E, et al. · Cochrane Database of Systematic Reviews · 2013 · Cochrane Library

Acute Respiratory InfectionsAMSTAR 2: not assessed
SoF tableOnly the outcomes this review put in its Summary of Findings table are listed (the Cochrane Handbook caps them at about seven per comparison). Its other analyses are not shown here.
Questions
6
current version
GRADE rated
6
No studies
0
Included studies
NR
No studies 0 · 0%Ungraded 0 · 0%Very low 2 · 33.3%Low 4 · 66.7%Moderate 0 · 0%High 0 · 0%

Ungraded means an effect was reported without a GRADE rating; it is not a gap. No studies means the review found nothing to answer the question. The six categories are a display order, not a score.

Questions and results

P. sidoides for the treatment of acute bronchitis in adults

Population: adults with acute bronchitis
2 questions
OutcomeEffectEvidenceStatus / GRADE
Failure to recover by day 7 (complete resolution of all symptoms) ‐ liquid preparation
RR 0.66 [0.52, 0.83]2 studies · 341 participantsLow
Downgraded: risk of bias, inconsistency, publication bias
Failure to recover by day 7 (complete resolution of all symptoms) ‐ tablet preparation
RR 0.95 [0.91, 0.99]1 study · 405 participantsLow
Downgraded: risk of bias, imprecision, publication bias

P. sidoides for treating acute bronchitis in children

Population: children with acute bronchitis
2 questions
OutcomeEffectEvidenceStatus / GRADE
Failure to recover by day 7 (complete resolution of all symptoms) ‐ liquid preparation
RR 0.82 [0.77, 0.88]2 studies · 420 participantsLow
Downgraded: risk of bias, publication bias
Failure to recover by day 7 (complete resolution of all symptoms) ‐ tablet preparation
RR 0.96 [0.89, 1.03]1 study · 399 participantsLow
Downgraded: risk of bias

P. sidoides versus placebo for treating acute sinusitis in adults

Population: adults with acute sinusitis
1 question
OutcomeEffectEvidenceStatus / GRADE
Failure to recover by day 21 (complete resolution of all symptoms)
P. sidoides vs placebo
RR 0.43 [0.3, 0.62]1 study · 103 participantsVery low
Downgraded: risk of bias, imprecision, publication bias

P. sidoides for common cold in adults

Population: adults with common cold
1 question
OutcomeEffectEvidenceStatus / GRADE
Failure to recover by day 5 (complete resolution of all symptoms)
RR 0.96 [0.9, 1.03]1 study · 103 participantsVery low
Downgraded: risk of bias, publication bias