Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Injuries · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 14.3%Low 5 · 71.4%Moderate 1 · 14.3%High 0 · 0%

All‐cause mortality

Continuous showed no clear difference in all‐cause mortality compared with intermittent Antibiotic Infusions (moderate certainty).

1 finding from 1 review

Continuous versus intermittent infusions of antibiotics for the treatment of severe acute infections 2013 · Cochrane Headline outcomes only
RR 0.89 [0.67, 1.2]
19 studies · 1241 participants
Moderate

Infection recurrence

Continuous showed no clear difference in infection recurrence compared with intermittent Antibiotic Infusions (low certainty).

1 finding from 1 review

Clinical cure

Continuous showed no clear difference in clinical cure compared with intermittent Antibiotic Infusions (low certainty).

1 finding from 1 review

Super‐infection

Continuous showed no clear difference in super‐infection compared with intermittent Antibiotic Infusions (low certainty).

1 finding from 1 review

Serious adverse events

Continuous showed no clear difference in serious adverse events compared with intermittent Antibiotic Infusions (low certainty).

1 finding from 1 review

Withdrawals due to adverse events

Continuous showed no clear difference in withdrawal due to adverse events compared with intermittent Antibiotic Infusions (low certainty).

1 finding from 1 review

Adverse events

It is very uncertain whether continuous changes adverse events compared with intermittent Antibiotic Infusions (very low certainty).

1 finding from 1 review