Findings

What do systematic reviews say?

6 questions · 6 findings · 1 reviews

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 6 · 100%High 0 · 0%

Combination of anticholinergics + beta2‐agonists vs B2‐agonists alone

Time to regular dose of short‐acting beta2‐agonists (hours) · children hospitalised with an acute asthma exacerbation

1 finding from 1 review

Inhaled anticholinergics and short‐acting beta₂‐agonists versus short‐acting beta2‐agonists alone for children with… 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 269 participants
Moderate

Combination of anticholinergics + beta2‐agonists vs B2‐agonists alone

Length of hospital stay · children hospitalised with an acute asthma exacerbation

1 finding from 1 review

Inhaled anticholinergics and short‐acting beta₂‐agonists versus short‐acting beta2‐agonists alone for children with… 2014 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 327 participants
Moderate

Combination of anticholinergics + beta2‐agonists vs B2‐agonists alone

Asthma clinical scores · children hospitalised with an acute asthma exacerbation

Combination of anticholinergics + beta2‐agonists showed no clear difference in asthma clinical scores compared with beta2‐agonists alone (moderate certainty).

1 finding from 1 review

Inhaled anticholinergics and short‐acting beta₂‐agonists versus short‐acting beta2‐agonists alone for children with… 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 117 participants
Moderate

Combination of anticholinergics + beta2‐agonists vs B2‐agonists alone

Incidence of admissions to the ICU · children hospitalised with an acute asthma exacerbation

1 finding from 1 review

Inhaled anticholinergics and short‐acting beta₂‐agonists versus short‐acting beta2‐agonists alone for children with… 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 210 participants
Moderate

Combination of anticholinergics + beta2‐agonists vs B2‐agonists alone

Overall withdrawals · children hospitalised with an acute asthma exacerbation

Combination of anticholinergics + beta2‐agonists showed no clear difference in overall withdrawals compared with beta2‐agonists alone (moderate certainty).

1 finding from 1 review

Inhaled anticholinergics and short‐acting beta₂‐agonists versus short‐acting beta2‐agonists alone for children with… 2014 · Cochrane Headline outcomes only
OR 0.59 [0.27, 1.3]
2 studies · 294 participants
Moderate

Combination of anticholinergics + beta2‐agonists vs B2‐agonists alone

Adverse health events · children hospitalised with an acute asthma exacerbation

1 finding from 1 review

Inhaled anticholinergics and short‐acting beta₂‐agonists versus short‐acting beta2‐agonists alone for children with… 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 290 participants
Moderate