Findings

What do systematic reviews say?

3 questions · 4 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 1 · 25%Moderate 3 · 75%High 0 · 0%

All‐cause mortality; · Ventilator‐associated pneumonia

Carbapenems showed no clear difference in all‐cause mortality; compared with non‐carbapenems (moderate certainty).

1 finding from 1 review

Antibiotics for ventilator‐associated pneumonia 2016 · Cochrane Headline outcomes only
OR 0.59 [0.3, 1.19]
1 study · 253 participants
Moderate

Clinical cure · Ventilator‐associated pneumonia

Carbapenems probably leads to higher clinical cure (ITT) compared with non‐carbapenems (moderate certainty).

2 findings from 1 review

Antibiotics for ventilator‐associated pneumonia 2016 · Cochrane Headline outcomes only
OR 1.53 [1.11, 2.12]
3 studies · 598 participants
Moderate
Antibiotics for ventilator‐associated pneumonia 2016 · Cochrane Headline outcomes only
OR 2.29 [1.19, 4.43]
2 studies · 163 participants
Moderate

Adverse events · Ventilator‐associated pneumonia

Carbapenems showed no clear difference in adverse events compared with non‐carbapenems (low certainty).

1 finding from 1 review

Antibiotics for ventilator‐associated pneumonia 2016 · Cochrane Headline outcomes only
OR 0.78 [0.56, 1.09]
3 studies · 1510 participants
Low