Findings

What do systematic reviews say?

7 questions · 7 findings · 1 reviews · Musculoskeletal

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No studies found 0 · 0%GRADE not reported 1 · 14.3%Very low 0 · 0%Low 3 · 42.9%Moderate 3 · 42.9%High 0 · 0%

Calcium channel blockers vs placebo

Migraine frequency Number of attacks · patients with Raynaud's phenomenon

1 finding from 1 review

Calcium channel blockers for primary and secondary Raynaud's phenomenon 2017 · Cochrane Headline outcomes only
no estimate extracted
23 studies · 528 participants
Moderate

Calcium channel blockers vs placebo

Duration of attacks · patients with Raynaud's phenomenon

1 finding from 1 review

Calcium channel blockers for primary and secondary Raynaud's phenomenon 2017 · Cochrane Headline outcomes only
no estimate extracted
6 studies · 69 participants
Low

Calcium channel blockers vs placebo

Severity of attacks · patients with Raynaud's phenomenon

1 finding from 1 review

Calcium channel blockers for primary and secondary Raynaud's phenomenon 2017 · Cochrane Headline outcomes only
no estimate extracted
18 studies · 415 participants
Moderate

Calcium channel blockers vs placebo

Pain intensity (0‐10cm visual analogue scale) · patients with Raynaud's phenomenon

1 finding from 1 review

Calcium channel blockers for primary and secondary Raynaud's phenomenon 2017 · Cochrane Headline outcomes only
no estimate extracted
4 studies · 62 participants
Low

Calcium channel blockers vs placebo

Patient global Disability due to Raynaud's assessed on a 10‐cm visual analogue scale (0 = no disability, 10 = maximal disability) · patients with Raynaud's phenomenon

1 finding from 1 review

Calcium channel blockers for primary and secondary Raynaud's phenomenon 2017 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 92 participants
Moderate

Calcium channel blockers vs placebo

Withdrawals due to adverse events · patients with Raynaud's phenomenon

Calcium channel blockers showed no clear difference in number of withdrawals due to adverse events Number of participants… compared with placebo (low certainty).

1 finding from 1 review

Calcium channel blockers for primary and secondary Raynaud's phenomenon 2017 · Cochrane Headline outcomes only
RR 1.3 [0.51, 3.33]
2 studies · 63 participants
Low

Calcium channel blockers vs placebo

Serious adverse events Number of participants who died or withdrew and were hospitalized as a result of adverse effects of treatment · patients with Raynaud's phenomenon

1 finding from 1 review

Calcium channel blockers for primary and secondary Raynaud's phenomenon 2017 · Cochrane Headline outcomes only
no estimate extracted
0 studies · 0 participants
GRADE not reported