Findings

What do systematic reviews say?

4 questions · 4 findings · 1 reviews

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 0 · 0%Moderate 0 · 0%High 4 · 100%

Overall survival† · people with cutaneous melanoma

Biochemotherapy showed no clear difference in overall survival† compared with chemotherapy (high certainty).

1 finding from 1 review

Systemic treatments for metastatic cutaneous melanoma 2018 · Cochrane Headline outcomes only
HR 0.94 [0.84, 1.06]
1317 participants
High

Progression‐free survival · people with cutaneous melanoma

Biochemotherapy leads to lower progression‐free survival† compared with chemotherapy (high certainty).

1 finding from 1 review

Systemic treatments for metastatic cutaneous melanoma 2018 · Cochrane Headline outcomes only
HR 0.9 [0.83, 0.99]
964 participants
High

Tumour response · people with cutaneous melanoma

Biochemotherapy leads to higher tumour response compared with chemotherapy (high certainty).

1 finding from 1 review

Systemic treatments for metastatic cutaneous melanoma 2018 · Cochrane Headline outcomes only
RR 1.36 [1.12, 1.66]
770 participants
High

Toxicity (≥ G3) · people with cutaneous melanoma

Biochemotherapy leads to higher toxicity (≥ G3) compared with chemotherapy (high certainty).

1 finding from 1 review

Systemic treatments for metastatic cutaneous melanoma 2018 · Cochrane Headline outcomes only
RR 1.35 [1.14, 1.61]
631 participants
High