Findings

What do systematic reviews say?

13 questions · 13 findings · 2 reviews · Infectious Diseases

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No studies found 3 · 23.1%GRADE not reported 0 · 0%Very low 2 · 15.4%Low 5 · 38.5%Moderate 3 · 23.1%High 0 · 0%

Azithromycin vs erythromycin

Stool volume · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 172 participants
Moderate

Azithromycin vs erythromycin

Bacteriological failure · Adults and children with cholera diarrhoea

Azithromycin showed no clear difference in bacteriological failure compared with erythromycin (low certainty).

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
RR 1.56 [0.8, 3.02]
2 studies · 179 participants
Low

Azithromycin vs ciprofloxacin

Duration of diarrhoea · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 375 participants
Moderate

Azithromycin vs ciprofloxacin

Stool volume · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
1 study · 195 participants
Low

Azithromycin vs ciprofloxacin

Bacteriological failure · Adults and children with cholera diarrhoea

Azithromycin may leads to lower bacteriological failure compared with ciprofloxacin (low certainty).

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
RR 0.23 [0.16, 0.34]
2 studies · 375 participants
Low

Azithromycin vs erythromycin

Duration of diarrhoea · Adults and children with cholera diarrhoea

1 finding from 1 review

Antimicrobial drugs for treating cholera 2014 · Cochrane Headline outcomes only
no estimate extracted
2 studies · 179 participants
Moderate

Ceftriaxone vs azithromycin

Relapse · children under 18 years of age with enteric fever

It is very uncertain whether ceftriaxone changes relapse compared with azithromycin (very low certainty).

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
RR 10.05 [1.93, 52.38]
3 studies · 185 participants
Very low

Ceftriaxone vs azithromycin

Time to defervescence · children under 18 years of age with enteric fever

Ceftriaxone showed no clear difference in time to defervescence compared with azithromycin (low certainty).

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
3 studies · 196 participants
Low

Ceftriaxone vs azithromycin

Length of hospital stay · children under 18 years of age with enteric fever

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ceftriaxone vs azithromycin

Convalescent faecal carriage · children under 18 years of age with enteric fever

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ceftriaxone vs azithromycin

Serious adverse events · children under 18 years of age with enteric fever

The review found no eligible studies for this question.

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
no estimate extracted
Studies not reported
No studies found

Ceftriaxone vs azithromycin

Clinical failure · children under 18 years of age with enteric fever

Ceftriaxone showed no clear difference in clinical failure compared with azithromycin (low certainty).

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
RR 0.42 [0.11, 1.57]
3 studies · 196 participants
Low

Ceftriaxone vs azithromycin

Microbiological failure · children under 18 years of age with enteric fever

It is very uncertain whether ceftriaxone changes microbiological failure compared with azithromycin (very low certainty).

1 finding from 1 review

Treatment of enteric fever (typhoid and paratyphoid fever) with cephalosporins 2022 · Cochrane Headline outcomes only
RR 1.95 [0.36, 10.64]
3 studies · 196 participants
Very low