What do systematic reviews say?

Any CNTF vs placebo

Any CNTF showed no clear difference in deaths compared with placebo (high certainty).

• Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease 2004 · Cochrane Headline outcomes only
  RR 1.07 [0.81, 1.41]
  2 studies · 1300 participants
  High

Any CNTF vs placebo

• Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease 2004 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1300 participants
  High

Any CNTF vs placebo

• Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease 2004 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 1300 participants
  High

Any CNTF vs placebo

• Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease 2004 · Cochrane Headline outcomes only
  no estimate extracted
  1 study · 503 participants
  High

Any CNTF vs placebo

Any CNTF showed no clear difference in asthenia compared with placebo (high certainty).

• Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease 2004 · Cochrane Headline outcomes only
  RR 1.02 [0.81, 1.28]
  1 study · 570 participants
  High

Any CNTF vs placebo

Any CNTF showed no clear difference in nausea compared with placebo (high certainty).

• Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease 2004 · Cochrane Headline outcomes only
  RR 1.35 [0.92, 1.99]
  1 study · 570 participants
  High

Any CNTF vs placebo

Any CNTF showed no clear difference in increased salivation compared with placebo (high certainty).

• Ciliary neurotrophic factor (CNTF) for amyotrophic lateral sclerosis or motor neuron disease 2004 · Cochrane Headline outcomes only
  RR 1.08 [0.78, 1.5]
  1 study · 570 participants
  High