Findings

What do systematic reviews say?

5 questions · 5 findings · 1 reviews · Anaesthesia

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No studies found 0 · 0%GRADE not reported 0 · 0%Very low 0 · 0%Low 4 · 80%Moderate 1 · 20%High 0 · 0%

Continuation vs discontinuation of antiplatelet therapy

Mortality within the longest · adults undergoing non‐cardiac surgery

Continuation showed no clear difference in all‐cause mortality (at longest compared with discontinuation of antiplatelet therapy (low certainty).

1 finding from 1 review

Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing… 2018 · Cochrane Headline outcomes only
RR 1.21 [0.34, 4.27]
5 studies · 659 participants
Low

Continuation vs discontinuation of antiplatelet therapy

All‐cause mortality (up to 30 days) · adults undergoing non‐cardiac surgery

Continuation showed no clear difference in all‐cause mortality (up to 30 days) compared with discontinuation of antiplatelet therapy (low certainty).

1 finding from 1 review

Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing… 2018 · Cochrane Headline outcomes only
RR 1.21 [0.34, 4.27]
4 studies · 616 participants
Low

Continuation vs discontinuation of antiplatelet therapy

Blood loss requiring transfusion of blood products (intraoperatively and postoperatively) · adults undergoing non‐cardiac surgery

Continuation showed no clear difference in blood loss requiring transfusion of blood products (intraoperatively… compared with discontinuation of antiplatelet therapy (moderate certainty).

1 finding from 1 review

Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing… 2018 · Cochrane Headline outcomes only
RR 1.37 [0.83, 2.26]
4 studies · 368 participants
Moderate

Continuation vs discontinuation of antiplatelet therapy

Blood loss requiring further surgery (intraoperatively and postoperatively) · adults undergoing non‐cardiac surgery

Continuation showed no clear difference in blood loss requiring further surgery (intraoperatively and… compared with discontinuation of antiplatelet therapy (low certainty).

1 finding from 1 review

Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing… 2018 · Cochrane Headline outcomes only
RR 1.54 [0.31, 7.58]
4 studies · 368 participants
Low

Continuation vs discontinuation of antiplatelet therapy

Ischaemic events: peripheral thrombosis, cerebral myocardial infarction (within 30 days of surgery) · adults undergoing non‐cardiac surgery

Continuation showed no clear difference in ischaemic events: peripheral thrombosis, cerebral myocardial… compared with discontinuation of antiplatelet therapy (low certainty).

1 finding from 1 review

Continuation versus discontinuation of antiplatelet therapy for bleeding and ischaemic events in adults undergoing… 2018 · Cochrane Headline outcomes only
RR 0.67 [0.25, 1.77]
4 studies · 616 participants
Low