Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

14 questions · 14 findings · 2 reviews · Stroke

No studies found 3 · 21.4%GRADE not reported 0 · 0%Very low 5 · 35.7%Low 0 · 0%Moderate 6 · 42.9%High 0 · 0%

Antiplatelet drug vs control

Recurrent ischaemic or unknown stroke during treatment period · acute ischaemic stroke

It is very uncertain whether antiplatelet drug changes recurrent ischaemic/unknown stroke during treatment period compared with control (very low certainty).

1 finding from 1 review

Antiplatelet drug vs control

Symptomatic intracranial haemorrhage during treatment period · acute ischaemic stroke

It is very uncertain whether antiplatelet drug changes symptomatic intracranial haemorrhage during treatment period compared with control (very low certainty).

1 finding from 1 review

Antiplatelet drug vs control

Major extracranial haemorrhage during treatment period · acute ischaemic stroke

It is very uncertain whether antiplatelet drug changes major extracranial haemorrhage during treatment period compared with control (very low certainty).

1 finding from 1 review

Antiplatelet drug vs control

Complete recovery from stroke (post hoc) · acute ischaemic stroke

Antiplatelet drug probably leads to higher complete recovery from stroke (post hoc) compared with control (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Platelet transfusion vs open control

Death or dependence (mRS 4 to 6) at day 90 · adults with acute spontaneous intracerebral haemorrhage associated with antiplatelet drug use

Summary of findings table ‐ Platelet transfusion probably leads to higher death or dependence (mRS 4–6) compared with open control (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Platelet transfusion vs open control

Intracerebral haemorrhage expansion by 24 hours · adults with acute spontaneous intracerebral haemorrhage associated with antiplatelet drug use

Summary of findings table ‐ Platelet transfusion showed no clear difference in intracerebral haemorrhage expansion by 24 hours compared with open control (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Platelet transfusion vs open control

All serious adverse events · adults with acute spontaneous intracerebral haemorrhage associated with antiplatelet drug use

Summary of findings table ‐ Platelet transfusion showed no clear difference in all serious adverse events compared with open control (moderate certainty).

1 finding from 1 review

Summary of findings table ‐ Platelet transfusion vs open control

Death from any cause · adults with acute spontaneous intracerebral haemorrhage associated with antiplatelet drug use

Summary of findings table ‐ Platelet transfusion showed no clear difference in death from any cause compared with open control (moderate certainty).

1 finding from 1 review