What do systematic reviews say?

Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing

Chlorhexidine dressing following alcohol cleansing showed no clear difference in sepsis without a source compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).

• Antimicrobial dressings for the prevention of catheter‐related infections in newborn infants with central venous… 2016 · Cochrane Headline outcomes only
  RR 1.06 [0.75, 1.52]
  1 study · 705 participants
  Moderate

Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing

Chlorhexidine dressing following alcohol cleansing showed no clear difference in catheter‐related blood stream infection compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).

• Antimicrobial dressings for the prevention of catheter‐related infections in newborn infants with central venous… 2016 · Cochrane Headline outcomes only
  RR 1.18 [0.53, 2.65]
  1 study · 655 participants
  Moderate

Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing

Chlorhexidine dressing following alcohol cleansing probably leads to lower catheter colonisation compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).

• Antimicrobial dressings for the prevention of catheter‐related infections in newborn infants with central venous… 2016 · Cochrane Headline outcomes only
  RR 0.62 [0.45, 0.86]
  1 study · 655 participants
  Moderate

Chlorhexidine dressing following alcohol cleansing vs polyurethane dressing following aqueous povidone‐iodine cleansing

Chlorhexidine dressing following alcohol cleansing probably leads to higher adverse effects: contact dermatitis compared with polyurethane dressing following aqueous povidone‐iodine cleansing (moderate certainty).

• Antimicrobial dressings for the prevention of catheter‐related infections in newborn infants with central venous… 2016 · Cochrane Headline outcomes only
  RR 43.06 [2.61, 710.44]
  1 study · 670 participants
  Moderate

Silver‐alginate dressing vs control

Silver‐alginate dressing showed no clear difference in CRBSI ‐ Unit of analysis: infants Clinical and microbiological methods compared with control (moderate certainty).

• Antimicrobial dressings for the prevention of catheter‐related infections in newborn infants with central venous… 2016 · Cochrane Headline outcomes only
  RR 0.5 [0.14, 1.78]
  1 study · 50 participants
  Moderate

Silver‐alginate dressing vs control

Silver‐alginate dressing showed no clear difference in CRBSI ‐ Unit of analysis: catheters Clinial and microbiological… compared with control (moderate certainty).

• Antimicrobial dressings for the prevention of catheter‐related infections in newborn infants with central venous… 2016 · Cochrane Headline outcomes only
  RR 0.72 [0.27, 1.89]
  1 study · 118 participants
  Moderate

Silver‐alginate dressing vs control

Silver‐alginate dressing showed no clear difference in mortality Clinial assessment compared with control (moderate certainty).

• Antimicrobial dressings for the prevention of catheter‐related infections in newborn infants with central venous… 2016 · Cochrane Headline outcomes only
  RR 0.55 [0.15, 2.05]
  2 studies · 150 participants
  Moderate

Silver‐alginate dressing vs control

• Antimicrobial dressings for the prevention of catheter‐related infections in newborn infants with central venous… 2016 · Cochrane Headline outcomes only
  no estimate extracted
  2 studies · 150 participants
  GRADE not reported