Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

32 questions · 32 findings · 2 reviews · Heart · Headline outcomes only

No studies found 0 · 0%GRADE not reported 0 · 0%Very low 1 · 3.1%Low 31 · 96.9%Moderate 0 · 0%High 0 · 0%

Monoclonal antibody vs polyclonal antibody

Post‐transplantation lymphoproliferative disorder Number of participants diagnosed with PTLD · heart transplant recipients

Monoclonal antibody showed no clear difference in post‐transplantation lymphoproliferative disorder Number of… compared with polyclonal antibody (low certainty).

1 finding from 1 review

Interleukin‐2 RA induction vs monoclonal antibody induction

Acute rejection Acute rejection grade 3A or more verified by biopsy · heart transplant recipients

Interleukin‐2 RA induction showed no clear difference in acute rejection Acute rejection grade 3A or more verified by biopsy compared with monoclonal antibody induction (low certainty).

1 finding from 1 review

Interleukin‐2 RA induction vs monoclonal antibody induction

Infection Number of participants diagnosed with infection · heart transplant recipients

Interleukin‐2 RA induction showed no clear difference in infection Number of participants diagnosed with infection compared with monoclonal antibody induction (low certainty).

1 finding from 1 review

Interleukin‐2 RA induction vs monoclonal antibody induction

Post‐transplantation lymphoproliferative disorder Number of participants diagnosed with PTLD · heart transplant recipients

Interleukin‐2 RA induction showed no clear difference in post‐transplantation lymphoproliferative disorder Number of… compared with monoclonal antibody induction (low certainty).

1 finding from 1 review

Interleukin‐2 RA vs polyclonal antibody induction

Acute rejection Acute rejection grade 3A or more verified by biopsy · heart transplant recipients

Interleukin‐2 RA may leads to higher acute rejection Acute rejection grade 3A or more verified by biopsy compared with polyclonal antibody induction (low certainty).

1 finding from 1 review