Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

155 questions · 166 findings · 21 reviews

No studies found 10 · 6%GRADE not reported 19 · 11.4%Very low 32 · 19.3%Low 65 · 39.2%Moderate 34 · 20.5%High 6 · 3.6%

Antibody vs other antibody (stratified by antibody type)

Failure of acute rejection reversal · kidney transplant recipients: steroid‐resistant rejection episodes

Antibody showed no clear difference in failure of acute rejection reversal compared with other antibody (stratified by antibody type) (low certainty).

1 finding from 1 review

Antibody vs other antibody (stratified by antibody type)

Recurrent rejection · kidney transplant recipients: steroid‐resistant rejection episodes

Antibody showed no clear difference in recurrent rejection compared with other antibody (stratified by antibody type) (low certainty).

1 finding from 1 review

Antibody vs other antibody (stratified by antibody type)

Graft loss censored for death · kidney transplant recipients: steroid‐resistant rejection episodes

Antibody showed no clear difference in graft loss censored for death compared with other antibody (stratified by antibody type) (low certainty).

1 finding from 1 review

Antibody vs other antibody (stratified by antibody type)

Graft loss or death with a functioning graft · kidney transplant recipients: steroid‐resistant rejection episodes

Antibody showed no clear difference in graft loss or death with a functioning graft compared with other antibody (stratified by antibody type) (low certainty).

1 finding from 1 review

Antibody vs other antibody (stratified by antibody type)

Adverse effects ‐ Bacterial infection clinical assessment · kidney transplant recipients: steroid‐resistant rejection episodes

It is very uncertain whether antibody changes treatment adverse events: bacterial infection compared with other antibody (stratified by antibody type) (very low certainty).

1 finding from 1 review

Monoclonal antibody vs polyclonal antibody

Post‐transplantation lymphoproliferative disorder Number of participants diagnosed with PTLD · heart transplant recipients

Monoclonal antibody showed no clear difference in post‐transplantation lymphoproliferative disorder Number of… compared with polyclonal antibody (low certainty).

1 finding from 1 review