Findings

What do systematic reviews say?

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Evidence found and GRADE certainty

13 questions · 13 findings · 2 reviews · Kidney and Transplant

No studies found 1 · 7.7%GRADE not reported 0 · 0%Very low 8 · 61.5%Low 1 · 7.7%Moderate 3 · 23.1%High 0 · 0%

Short duration (3 to 4 days) vs long duration (7 to 14 days) IV therapy

Persistent renal damage at 3 to 6 months: all included children with acute pyelonephritis · children with acute pyelonephritis

Short duration (3 to 4 days) showed no clear difference in persistent renal damage at 3 to 6 months: all included children with… compared with long duration (7 to 14 days) IV therapy (moderate certainty).

1 finding from 1 review

Short duration (3 to 4 days) vs long duration (7 to 14 days) IV therapy

Persistent renal damage at 3 to 6 months: children with initial renal parenchymal damage on initial DMSA scan · children with acute pyelonephritis

Short duration (3 to 4 days) showed no clear difference in persistent renal damage at 3 to 6 months: children with initial… compared with long duration (7 to 14 days) IV therapy (moderate certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Surgical site infections: liver transplant recipients Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes surgical site infections: liver transplant recipients Time frame: 30… compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Graft loss including death · solid organ transplant recipients

It is very uncertain whether extended changes graft loss (including death with functioning graft) Time frame: 30… compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Other infection: septicaemia Time frame: 2 to 6 weeks · solid organ transplant recipients

It is very uncertain whether extended changes other infection: septicaemia Time frame: 30 days compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Other infection: pneumonia Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes other infection: pneumonia Time frame: 30 days compared with short duration antibiotics (very low certainty).

1 finding from 1 review

Extended vs short duration antibiotics

Surgical site infections: kidney transplant recipients Time frame: 30 days · solid organ transplant recipients

It is very uncertain whether extended changes surgical site infections: kidney transplant recipients Time frame:… compared with short duration antibiotics (very low certainty).

1 finding from 1 review